Abstract
No current non-invasive method is capable of assessing the efficacy of brain tumor therapy early during treatment. We outline an approach that evaluates tumor activity via statistical analysis of vessel shape using vessels segmented from MRA. This report is the first to describe the changes in vessel shape that occur during treatment of metastatic brain tumors as assessed by sequential MRA. In this preliminary study of 16 patients undergoing treatment for metastatic breast cancer we conclude that vessel shape may predict tumor response several months in advance of traditional methods.
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Keywords
- Metastatic Brain Tumor
- Choroid Plexus Carcinoma
- Vessel Analysis
- Carcinomatous Meningitis
- Vessel Tortuosity
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Bullitt, E. et al. (2006). Tumor Therapeutic Response and Vessel Tortuosity: Preliminary Report in Metastatic Breast Cancer. In: Larsen, R., Nielsen, M., Sporring, J. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006. MICCAI 2006. Lecture Notes in Computer Science, vol 4191. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11866763_69
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DOI: https://doi.org/10.1007/11866763_69
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-44727-6
Online ISBN: 978-3-540-44728-3
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