Skip to main content

A Novel Test Statistic for the Identification of Local Selective Sweeps Based on Microsatellite Gene Diversity

  • Chapter
Selective Sweep

Part of the book series: Molecular Biology Intelligence Unit ((MBIU))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Hudson RR, Bailey K, Skarecky D et al. Evidence for positive selection in the superoxide dismutase (Sod) region of Drosophila melanogaster. Genetics 1994; 136:1329–1340.

    PubMed  CAS  Google Scholar 

  2. Ferea TL, Botstein D, Brown PO et al. Systematic changes in gene expression patterns following adaptive evolution in yeast. PNAS 1999; 96(17):9721–9726.

    Article  PubMed  CAS  Google Scholar 

  3. Toma DP, White KP, Hirsch J et al. Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait. Nat Genet 2002; 31(4):349–353.

    PubMed  CAS  Google Scholar 

  4. Gould SJ, Lewontin RC. The spandrels of San Marco and the Panglossian paradigm: A critique of the adaptationist programme. Proc Roy Soc Lond B 1979; 205:581–598.

    Article  CAS  Google Scholar 

  5. Maynard Smith J, Haigh J. The hitch-hiking effect of a favorable gene. Genet Res 1974; 23:23–35.

    Google Scholar 

  6. Harr B, Kauer M, Schlötterer C. Hitchhiking mapping—a population based fine mapping strategy for adaptive mutations in D melanogaster. PNAS 2002; 99:12949–12954.

    Article  PubMed  CAS  Google Scholar 

  7. Kim Y, Stephan W. Detecting a local signature of genetic hitchhiking along a recombining chromosome. Genetics 2002; 160(2):765–777.

    PubMed  CAS  Google Scholar 

  8. Schlötterer C. Towards a molecular characterization of adaptation in local populations. Curr Opin Genet Dev 2002; 12(6):683–7.

    Article  PubMed  Google Scholar 

  9. Kohn MH, Pelz HJ, Wayne RK. Natural selection mapping of the warfarin-resistance gene. PNAS 2000; 97(14):7911–7915.

    Article  PubMed  CAS  Google Scholar 

  10. Wootton JC, Feng X, Ferdig MT et al. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature 2002; 418(6895):320–323.

    Article  PubMed  CAS  Google Scholar 

  11. Vigouroux Y, McMullen M, Hittinger CT et al. Identifying genes of agronomic importance in maize by screening microsatellites for evidence of selection during domestication. PNAS 2002; 99(15):9650–9655.

    Article  PubMed  CAS  Google Scholar 

  12. Payseur BA, Cutter AD, Nachman MW. Searching for evidence of positive selection in the human genome using patterns of microsatellite variability. Mol Biol Evol 2002; 19(7):1143–1153.

    PubMed  CAS  Google Scholar 

  13. Schlötterer C, Vogl C, Tautz D. Polymorphism and locus-specific effects on polymorphism at microsatellite loci in natural Drosophila melanogaster populations. Genetics 1997; 146:309–320.

    PubMed  Google Scholar 

  14. Schlötterer C. A microsatellite-based multilocus screen for the identification of local selective sweeps. Genetics 2002; 160(2):753–763.

    PubMed  Google Scholar 

  15. Harr B, Zangerl B, Brem G et al. Conservation of locus specific microsatellite variability across species: A comparison of two Drosophila sibling species D melanogaster and D simulans. MBE 1998; 15:176–184.

    CAS  Google Scholar 

  16. Di Rienzo A, Donnelly P, Toomajian C, et al. Heterogeneity of microsatellite mutations within and between loci and implications for human demographic histories. Genetics 1998; 148:1269–1284.

    PubMed  Google Scholar 

  17. Hudson RR. Gene geneologies and the coalescent process. Oxf Surv Evol Biol 1990; 7:1–44.

    Google Scholar 

  18. Ohta T, Kimura M. A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population. Genet Res 1973; 22:201–204.

    Article  Google Scholar 

  19. Di Rienzo A, Peterson AC, Garza JC et al. Mutational processes of simple-sequence repeat loci in human populations. PNAS 1994; 91:3166–3170.

    Article  PubMed  Google Scholar 

  20. Lynch M, Walsh B. Genetics and analysis of quantitative traits. Sunderland: Sinauer Associates, 1998.

    Google Scholar 

  21. Wiehe T. The effect of selective sweeps on the variance of the allele distribution of a linked multi-allele locus-hitchhiking of microsatellites. Theor Popul Biol 1998; 53:272–283.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Eurekah.com and Kluwer Academic/Plenum Publishers

About this chapter

Cite this chapter

Schlötterer, C., Dieringer, D. (2005). A Novel Test Statistic for the Identification of Local Selective Sweeps Based on Microsatellite Gene Diversity. In: Nurminsky, D. (eds) Selective Sweep. Molecular Biology Intelligence Unit. Springer, Boston, MA. https://doi.org/10.1007/0-387-27651-3_5

Download citation

Publish with us

Policies and ethics