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Selective Sweep

  • Dmitry Nurminsky

Part of the Molecular Biology Intelligence Unit book series (MBIU)

Table of contents

  1. Front Matter
    Pages i-viii
  2. John Parsch, Colin D. Meiklejohn, Daniel L. Hartl
    Pages 1-12
  3. Alberto Civetta, Rama S. Singh
    Pages 13-21
  4. Rob J. Kulathinal, Stanley A. Sawyer, Carlos D. Bustamante, Dmitry Nurminsky, Rita Ponce, José M. Ranz et al.
    Pages 22-33
  5. Frantz Depaulis, Sylvain Mousset, Michel Veuille
    Pages 34-54
  6. Justin C. Fay, Chung-I Wu
    Pages 65-77
  7. Thomas Wiehe, Karl Schmid, Wolfgang Stephan
    Pages 104-117
  8. Back Matter
    Pages 119-121

About this book

Introduction

Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole genome, thus providing the tool for effective identification of loci that are under strong pressure of positive selection. For this reason, the studies of selective sweep, which formerly were of interest mostly to evolutionists, have become widely recognized and appreciated by the large biological community involved in identification of the targets of selection during speciation, host/pathogen interactions, and resistance to chemical agents.

Keywords

DNA Haplotype Malaria chromosome evolution genes

Editors and affiliations

  • Dmitry Nurminsky
    • 1
  1. 1.Department of Anatomy and Cellular BiologyTufts University School of MedicineBostonUSA

Bibliographic information