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Simultaneous Determination of Inorganic Cations and Anions in Microchip Electrophoresis Using High-voltage Relays

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Abstract

A new and simple method for the simultaneous determination of cations and anions by microchip electrophoresis with capacitively coupled contactless conductivity detection (ME-C4D) is described. The best analytical performance was found by applying a sinusoidal wave with 800 kHz frequency and 20 Vpp amplitude. An optimized background electrolyte (BGE) composed of 20 mM His/MES and 0.01 mM CTAB was chosen for the simultaneous analysis. Samples containing K+, Na+, and Li+ as the cations and Cl−, F− and PO43− as anions were analyzed simultaneously in a single run (within 3 min). The reproducibility obtained by the method was compared with those obtained in previous studies that had employed simultaneous analysis of anions and cations by ME-C4D. The proposed simultaneous determination method is inexpensive, simple, fast, easy to operate, and offers a high degree of integration.

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Acknowledgments

We are grateful for the funds provided by the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (SQ2015BA0800060).

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Authors and Affiliations

  1. Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, 230031, PR China

    Zhe Huang, Mingpeng Yang, Hui You & Yang Xie

  2. Department of Instruments Science and Engineering, University of Science and Technology of China, Hefei, 230026, PR China

    Zhe Huang, Mingpeng Yang, Hui You & Yang Xie

Authors
  1. Zhe Huang
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  2. Mingpeng Yang
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  3. Hui You
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  4. Yang Xie
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Correspondence to Hui You.

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Huang, Z., Yang, M., You, H. et al. Simultaneous Determination of Inorganic Cations and Anions in Microchip Electrophoresis Using High-voltage Relays. ANAL. SCI. 34, 801–805 (2018). https://doi.org/10.2116/analsci.18P022

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  • DOI: https://doi.org/10.2116/analsci.18P022

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