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Progress in the imaging of COPD: quantitative and functional evaluation

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Abstract

Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease, which has caused serious social and economic burden. The main characteristic of COPD is the heterogeneity of disease, manifesting as emphysema, functional small airways disease (fSAD) and large airway diseases. Imaging plays an important role in the evaluation of COPD. In this article, we summarized the recent advances in the imaging of COPD, especially in the quantitative and functional evaluations of the disease. Imaging provides the detailed anatomical, quantitative and function information, illustrates regional heterogeneity and spatial distribution, as well as provides microstructural assessment on the alveolar level. Especially, air trapping index (ATI), parametric response mapping (PRM), gas exchange and texture analysis facilitate the early diagnosis, phenotype classification, severity and therapeutic effect evaluation.

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Funding

This work was supported by the National Natural Science Foundation of China [Grant numbers 81871321, 81370035]; the National Key R&D Program of China [Grant numbers 2016YFE0103000, 2017YFC1308703].

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Authors and Affiliations

  1. Department of Radiology, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Road, Shanghai, 200003, China

    Li Fan, Xiuxiu Zhou, Yi Xia, Yu Guan, Di Zhang & Shiyuan Liu

  2. Department of Radiation Oncology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, No. 600 Yishan Road, Shanghai, 200233, China

    ZhaoBin Li

Authors
  1. Li Fan
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  2. Xiuxiu Zhou
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  3. Yi Xia
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  4. Yu Guan
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  5. Di Zhang
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  6. ZhaoBin Li
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  7. Shiyuan Liu
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Correspondence to ZhaoBin Li or Shiyuan Liu.

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Fan, L., Zhou, X., Xia, Y. et al. Progress in the imaging of COPD: quantitative and functional evaluation. Chin J Acad Radiol 1, 43–48 (2019). https://doi.org/10.1007/s42058-019-00007-0

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  • DOI: https://doi.org/10.1007/s42058-019-00007-0

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