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Functional Assessment of COPD

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Pulmonary Functional Imaging

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition with variable clinical and pathophysiologic features. Functional information of the lungs is important to understand the complex pathophysiology of COPD. With recent technical advances in the CT imaging and magnetic resonance imaging (MRI), various imaging techniques have been used for the evaluation of functional changes in COPD. The quantitative CT imaging can be used to objectively assess the severity of emphysema, airway wall changes, air trapping, and other comorbidities, which are correlated with functional aspect of COPD. The dual-energy CT imaging and functional MRI can directly assess and visualize the functional changes such as ventilation, perfusion, and ventilation–perfusion relationship with anatomically matched structural information of the lung in COPD. In this chapter, we will review the current technical status of functional imaging briefly, and focus on its clinical applications, limitations, and some of the most recent works in COPD.

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Authors and Affiliations

  1. Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Seoul, South Korea

    Hye Jeon Hwang, Sang Min Lee & Joon Beom Seo

  2. Division of Cardiothoracic Radiology, Department of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

    Joon Beom Seo

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  1. Department of Radiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

    Yoshiharu Ohno

  2. Department of Radiology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

    Hiroto Hatabu

  3. Diagnostic and Interventional Radiology German Center of Lung Research, Ruprecht-Karls-University Heidelberg, Heidelberg, Baden-WĂĽrttemberg, Germany

    Hans-Ulrich Kauczor

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Hwang, H.J., Lee, S.M., Seo, J.B. (2021). Functional Assessment of COPD. In: Ohno, Y., Hatabu, H., Kauczor, HU. (eds) Pulmonary Functional Imaging. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/978-3-030-43539-4_8

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