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β-Cryptoxanthin: Chemistry, Occurrence, and Potential Health Benefits

  • Natural Products: From Chemistry to Pharmacology (C Ho, Section Editor)
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Abstract

Purpose of Review

β-Cryptoxanthin is one of the most common carotenoids. With high concentrations in human serum and tissue, it is inversely associated with many life-threatening diseases. This paper presents a brief overview of the chemical properties and occurrence of β-cryptoxanthin and summarizes the recent trend in β-cryptoxanthin research.

Recent Findings

β-Cryptoxanthin is an oxygenated carotenoid common as both free and esterified forms in fruits and vegetables. The distribution of free β-cryptoxanthin and β-cryptoxanthin esters is dependent upon plant types and environmental conditions, such as season, processing techniques, and storage temperatures. The use of β-cryptoxanthin as a nutritional supplement, food additive, and food colorant have stimulated a variety of approaches to identify and quantify free β-cryptoxanthin and β-cryptoxanthin esters. Advances in analytic approaches, including high-performance liquid chromatography (HPLC) coupled with UV and mass spectrometry (MS), have been developed to analyze β-cryptoxanthin, especially the ester forms. In recent years, β-cryptoxanthin has been thought to play an import role in promoting human health, particularly among the population receiving β-cryptoxanthin as a supplement. Some research indicates that the bioavailability of β-cryptoxanthin in typical diets is greater than that of other major carotenoids, suggesting that β-cryptoxanthin-rich foods are probably good sources of carotenoids.

Summary

β-Cryptoxanthin provides various potential benefits for human health. The chemical structure, occurrence, and absorption of β-cryptoxanthin are discussed in this review. This review provides the latest major approaches used to identify and quantify β-cryptoxanthin. Additionally, various benefits, including provitamin A, anti-obesity effects, antioxidant activities, anti-inflammatory and anti-cancer activity, are summarized in this review.

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  1. Citrus Research & Education Center, University of Florida, 700 Experiment Station Rd., Lake Alfred, FL, 33850, USA

    Yanli Jiao, Laura Reuss & Yu Wang

  2. Food Science and Human Nutrition, University of Florida, 572 Newell Dr, Gainesville, FL, 32611, USA

    Yu Wang

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Jiao, Y., Reuss, L. & Wang, Y. β-Cryptoxanthin: Chemistry, Occurrence, and Potential Health Benefits. Curr Pharmacol Rep 5, 20–34 (2019). https://doi.org/10.1007/s40495-019-00168-7

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