Author Information

An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

A 46-year-old man exhibited no drug effect during treatment with venetoclax, azacitidine, fludarabine, cytarabine, idarubicin, etoposide, vincristine and vindesine for acute myeloid leukemia (AML). He exhibited lack of efficacy during treatment with fluconazole, micafungin, caspofungin for antifungal prophylaxis and amphotericin-B-liposomal, voriconazole for fungal infection caused by Candida guilliermondii and Blastobotrys mokoenaii [not all routes and dosages stated].