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Two-stage framework for optic disc segmentation and estimation of cup-to-disc ratio using deep learning technique

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Abstract

The accurate segmentation of retinal anatomies and pathology is a crucial task to diagnose and evaluate various metabolic and ophthalmic disorders such as diabetes, hypertension, glaucoma and other common diseases. The optic disc (OD) segmentation in fundus photography is the preliminary and essential activity for diagnosing retinal disorders. The conventional supervised methods follow multiple stages which consume more time and also the accuracy found to be deprived in majority of the cases. The potentiality of deep learning techniques, especially the fully convolutional neural architecture is adopted in this paper to perform OD segmentation in the initial stage and at a later stage image processing algorithms are used to estimate the cup-to-disc ratio. Using an optimal set of image processing operations the ground truth images were generated from the hand-labeled fundus images. The proposed U-Net architecture consisting of encoder and decoder blocks to capture the spatial information and to precise localization of OD respectively. The model performance was estimated in terms of Accuracy and Intersection over Union (IoU) indices. The proposed method attained an accuracy level of 99.7% and IoU of 87.9% which is superior when compared to the contemporary methods in literature.

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Availability of data and materials

The datasets were collected from six different sources: BinRushed and Magrabia: https://deepblue.lib.umich.edu/data/concern/data_sets/3b591905z. MESSIDOR: http://www.adcis.net/en/third-party/messidor/. DRIONS-DB: http://www.ia.uned.es/~ejcarmona/DRIONS-DB/BD/DRIONS-DB.rar. RIM-ONE: http://medimrg.webs.ull.es/research/downloads/. IDRiD: https://ieee-dataport.org/open-access/indian-diabetic-retinopathy-image-dataset-idrid.

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Kumar, E.S., Bindu, C.S. Two-stage framework for optic disc segmentation and estimation of cup-to-disc ratio using deep learning technique. J Ambient Intell Human Comput (2021). https://doi.org/10.1007/s12652-021-02977-5

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