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Vestibular Migraine Pathophysiology and Treatment: a Narrative Review

  • Episodic Migraine (S Parikh, Section Editor)
  • Published:
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Abstract

Purpose of Review

To review the diagnosis of vestibular migraine (VM) and update the clinician on the most recent developments in our understanding of its pathophysiology and treatment.

Recent Findings

Functional imaging studies have identified multiple regions of the brain with abnormal activity and connectivity in VM. There is evidence of abnormal sensory processing and integration in VM patients. Calcitonin gene-related peptide (CGRP) has also been found to play a role in trigeminal and vestibular nucleus pathways. Research into treatment modalities has identified several neuromodulation devices that may be effective in VM. There are a growing number of evidence-based preventive options for VM, including medications that target CGRP.

Summary

VM is best understood as a sensory processing disorder. CGRP appears to play a role, and further research is needed to fully understand its effects. Treatment options are expanding, but there is still a need for more randomly controlled trials in this area.

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  1. Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, 900 Walnut St., Ste 200, Philadelphia, PA, 19107, USA

    Claire E. J. Ceriani

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Ceriani, C.E.J. Vestibular Migraine Pathophysiology and Treatment: a Narrative Review. Curr Pain Headache Rep 28, 47–54 (2024). https://doi.org/10.1007/s11916-023-01182-7

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