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Role of Optical Coherence Tomography Angiography Imaging in Patients with Diabetes

  • Microvascular Complications—Retinopathy (R Channa, Section Editor)
  • Published:
Current Diabetes Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Ocular manifestations in patients with diabetes mellitus (DM) can present as microvascular changes. These microvascular changes can be challenging to identify on exams, and imaging technologies have commonly aided in the diagnosis and management of patients with DM. Optical coherence tomography angiography (OCTA) provides noninvasive image segmentation of various layers of the retina and choroid. Also, post-processing of images and associated quantitative measurements offer potential clinical enhancements. Our aim is to review the current evidence on the utility of OCTA for patients with DM.

Recent Findings

Research suggests OCTA to potentially provide potential clinical enhancements and alternative methods in detecting subclinical manifestation of diabetic retinopathy, staging diabetic retinopathy, management of diabetic macular edema, and monitoring of systemic markers in patients with diabetes mellitus.

Summary

OCTA is a promising but relatively new modality, and differences in terminology, research designs, and image processing techniques provide a difficult landscape to navigate. Standardization within further validation is needed to determine the extent of OCTA’s clinical utility, but the current literature suggests the potential for earlier detection of ocular manifestations in patients with DM, additional objective measurements for grading and management, and opportunity for additional biomarkers for treatment outcomes.

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  1. Department of Ophthalmology, University of North Carolina At Chapel Hill, Chapel Hill, NC, USA

    Patrick Le, Jason Zehden & Alice Yang Zhang

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Le, P., Zehden, J. & Zhang, A.Y. Role of Optical Coherence Tomography Angiography Imaging in Patients with Diabetes. Curr Diab Rep 21, 42 (2021). https://doi.org/10.1007/s11892-021-01405-4

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