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Visual surround suppression at the neural and perceptual levels

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Abstract

Surround suppression was initially identified as a phenomenon at the neural level in which stimuli outside the neuron’s receptive field alone cannot activate responses but can modulate neural responses to stimuli covered inside the receptive field. Subsequent studies showed that surround suppression is not only a critical property of neurons across species and brain areas but also has been found in visual perceptions. More importantly, surround suppression varies across individuals and shows significant differences between normal controls and patients with certain mental disorders. Here, we combined results from related literature and summarized the findings derived from physiological and psychophysical evidence. We first outline the basic properties of surround suppression in the visual system and perceptions. Then, we mainly summarize the differences in perceptual surround suppression among different human subjects. Our review suggests that there is no consensus regarding whether the strength of perceptual surround suppression could be used as an effective index to distinguish particular populations. Then, we summarized the similar mechanisms for surround suppression and cognitive impairments to further explore the potential clinical applications of surround suppression. A clearer understanding of the mechanisms of surround suppression in neural responses and perceptions is necessary for facilitating its clinical applications.

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Acknowledgements

This work was supported by Fundamental Research Funds for the Central Universities under Grant 2023JKF02ZK14 and National Science and Technology Innovation 2030 Major Program (2022ZD0204600).

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Authors and Affiliations

  1. School of Criminology, People’s Public Security University of China, Beijing, 100038, China

    Yang Li

  2. State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, 100875, China

    Weifeng Dai, Tian Wang, Yujie Wu, Fei Dou & Dajun Xing

  3. College of Life Sciences, Beijing Normal University, Beijing, 100875, China

    Tian Wang & Fei Dou

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Li, Y., Dai, W., Wang, T. et al. Visual surround suppression at the neural and perceptual levels. Cogn Neurodyn 18, 741–756 (2024). https://doi.org/10.1007/s11571-023-10027-3

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