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Synthesis and catalase-like activity of dimanganese complexes with phthalazine-based ligands

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Abstract

Dimanganese complexes Mn2 III(L1)(OAc)4 and Mn2 III(L2)(OAc)4 with the phthalazine-based ligands 1,4-di(2′-benzimidazolyl)aminophthalazine (H2L1) and 1,4-di(N-methyl-2′-benzimidazolyl)aminophthalazine (H2L2) have been prepared and characterized. The complexes accelerate the disproportionation of H2O2 into water and dioxygen in buffered aqueous solutions in a near-neutral pH range thus can be regarded as catalase models. Results of kinetic measurements indicate a similar mechanism for the two catalysts, but formation of the proposed peroxo-adduct intermediate is less favored for Mn2 III(L1)(OAc)4. It is presumed to be the reason for the lower rates for this catalyst even at higher pH.

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Acknowledgments

Financial support of the Hungarian National Research Fund (OTKA K67871, OTKA K75783, and OTKA PD75360) and COST is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, University of Pannonia, 8200, Veszprém, Hungary

    József Sándor Pap, Brigitta Horváth, Gábor Speier & József Kaizer

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  1. József Sándor Pap
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  2. Brigitta Horváth
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  3. Gábor Speier
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  4. József Kaizer
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Correspondence to József Kaizer.

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Pap, J.S., Horváth, B., Speier, G. et al. Synthesis and catalase-like activity of dimanganese complexes with phthalazine-based ligands. Transition Met Chem 36, 603–609 (2011). https://doi.org/10.1007/s11243-011-9508-9

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