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Cyanoacetylation of amines: recent advances in preparation methods and their synthetic uses in the formation of biologically active compounds

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Abstract

A systematic and comprehensive survey of the preparation methods of N-cyanoacetamides is discussed in this review. Also, the chemical reactivity and reactions of this class to obtain biologically active novel heterocyclic moieties is described.

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  1. Chemistry Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt

    Ahmed A. Fadda

  2. Chemistry Lab., Mansoura Fevers Hospital, Mansoura, Egypt

    Ramy Rabie

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  1. Ahmed A. Fadda
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Dedicated to the spirit of my father Mr. Rabie Shafek Ahmed and my Uncle Dr. Ragb El-Bendary, who had died in the months of October and November of 2014.

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Fadda, A.A., Rabie, R. Cyanoacetylation of amines: recent advances in preparation methods and their synthetic uses in the formation of biologically active compounds. Res Chem Intermed 42, 771–811 (2016). https://doi.org/10.1007/s11164-015-2055-9

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