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Voltammetric study of the antioxidant properties of catalase and superoxide dismutase

  • Structure of Chemical Compounds, Methods of Analysis and Process Control
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Pharmaceutical Chemistry Journal Aims and scope

The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms of the interaction of enzymes with reactive oxygen species are considered. Antioxidant activity criterion (IC50) for SOD and some copper complexes have been estimated by voltammetry and spectrophotometry.

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Authors and Affiliations

  1. Tomsk Polytechnical University, Tomsk, Russia

    E. I. Korotkova & O. I. Lipskikh

  2. Tomsk State University, Tomsk, Russia

    M. A. Kiseleva

  3. Siberian State Medical University, Tomsk, Russia

    V. V. Ivanov

Authors
  1. E. I. Korotkova
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  2. O. I. Lipskikh
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  3. M. A. Kiseleva
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  4. V. V. Ivanov
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Corresponding author

Correspondence to O. I. Lipskikh.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 8, pp. 45–48, August, 2008.

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Korotkova, E.I., Lipskikh, O.I., Kiseleva, M.A. et al. Voltammetric study of the antioxidant properties of catalase and superoxide dismutase. Pharm Chem J 42, 485–487 (2008). https://doi.org/10.1007/s11094-008-0156-0

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  • DOI: https://doi.org/10.1007/s11094-008-0156-0

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