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A new 4-Amino-7-Nitro-2,1,3-Benzoxadiazole (ANBD)-Based Fluorescent Probe for the Detection of Hg2+

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Abstract

Based on the photoinduced electron transfer (PET) principle, 4-amino-7-nitro-2,1,3-benzoxadiazole (ANBD) has been used as a fluorophore to develop a new fluorescent probe, 4-(2-N,N-dimethylthioacetamide)amino-7-nitro-2,1,3-benzoxadiazole (2), for the detection of Hg2+. Upon the addition of Hg2+, a 46-fold fluorescence enhancement occurs. Moreover the probe 2 exhibits a high selectivity and sensitivity to Hg2+, even in the presence of other common metal ions. Under optimal reaction conditions, a good linearity can be obtained in the range of 0.5–2.5 μM, and the detection limit is 0.05 μM. In addition, the desulfurization reaction mechanism is proposed based on electrospray ionization mass spectrum. The present study is not only a supplement to the detection method of Hg2+, but also a merit to the development of ANBD-based fluorescent probes.

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Acknowledgements

We gratefully acknowledge the financial support from the Natural Science Foundation of Hebei Province, China (No. B2013106116).

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Authors and Affiliations

  1. Shijiazhuang Center for Disease Control and Prevention, Shijiazhuang, 050011, China

    Ke Wang, Liling Cao, Guoping Lv, Xinfeng Dong & Yan He

  2. College of Chemistry and Material Science, Hebei Normal University, Shijiazhuang, 050024, China

    Xue Mao & Yongju Wei

Authors
  1. Ke Wang
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  2. Xue Mao
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  3. Liling Cao
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  4. Guoping Lv
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  6. Yan He
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Correspondence to Ke Wang or Yongju Wei.

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Wang, K., Mao, X., Cao, L. et al. A new 4-Amino-7-Nitro-2,1,3-Benzoxadiazole (ANBD)-Based Fluorescent Probe for the Detection of Hg2+ . J Fluoresc 27, 1739–1745 (2017). https://doi.org/10.1007/s10895-017-2112-4

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