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Cardiometabolic risk factors and mercury content in hair of women from a territory distant from mercury-rich geochemical zones (Cherepovets city, Northwest Russia)

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Abstract

For the first time in the Russian Federation, a study was conducted to determine the level of mercury in the hair of young and middle-aged women with or without metabolic syndrome (MS) and the Association of mercury content in hair with cardiometabolic risk factors. The studied cohort consisted of 387 women (204 with metabolic syndrome and 183 without metabolic syndrome as controls). The mercury content in the hair was determined by atomic absorption pyrolysis. The relationship between mercury in hair and cardiometabolic risk factors was evaluated using linear regression. Calculation of the odds ratio (OR) of the risk of metabolic syndrome among quartiles of mercury content in the hair was performed by multiple logistic regression. Hg concentrations in hair were higher in women with metabolic syndrome than without metabolic syndrome (Mean – 520; median – 360; versus Mean – 330; median – 260 µg/kg, P < 0.001). There is an increased risk of developing cardiometabolic syndrome in women, whose hair contain over 544 µg/kg of mercury. The results of this study indicate that the intake of Hg in the human body can be one of the factors that can increase the development of cardiometabolic risk.

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Authors and Affiliations

  1. Cherepovets State University, 5 Lunacharsky Pr., Cherepovets, Vologda region, 162600, Russia

    E. S. Ivanova, O. P. Shuvalova, L. S. Eltsova, V. T. Komov & A. I. Kornilova

  2. Papanin Institute for Biology of Inland Waters, Russian Academy of Sciences, 109, Borok, Nekouzskii raion, Yaroslavskaya Oblast, 152742, Russia

    V. T. Komov

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  1. E. S. Ivanova
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  2. O. P. Shuvalova
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  3. L. S. Eltsova
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  4. V. T. Komov
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  5. A. I. Kornilova
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Contributions

Ivanova E.S. contributed to conception and design of the study, drafting of the manuscript. Shuvalova O.P. contributed to data analysis. Eltsova L.S. contributed to conducting research, statistical data processing. Komov V.T. contributed to critical review of the article for important intellectual content and final approval for the publication of the manuscript. Kornilova A.I. contributed to statistical data processing. Ivanova E.S., Shuvalova O.P., Eltsova L.S., Komov V.T., Kornilova A.I. carried out the key stages of the experiment.

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Correspondence to L. S. Eltsova.

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Ethical approval

The program of this study was discussed and approved by the Bioethics Commission of Cherepovets State University and the Territorial Department of Health of the Vologda Oblast (No. 2–1 / 55, 18.01.2019).

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Ivanova, E.S., Shuvalova, O.P., Eltsova, L.S. et al. Cardiometabolic risk factors and mercury content in hair of women from a territory distant from mercury-rich geochemical zones (Cherepovets city, Northwest Russia). Environ Geochem Health 43, 4589–4599 (2021). https://doi.org/10.1007/s10653-021-00939-6

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