A new quassinoid, dehydrobruceantinol B (1), was isolated from the seeds of Brucea javanica, together with two known compounds, bruceantinol (2) and bruceine A (3). The structure of the new compound 1 was elucidated by advanced spectrometric methods, including HR-MS, UV, IR, 1D and 2D NMR experiments. The inhibitory effects of 1–3 on nitric oxide production in lipopolysaccharide-activated macrophages were also investigated in this study.
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This study is supported by the Department of Science and Technology of Liaoning Province (2020-MS-225).
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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2022, pp. 553–555.
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Li, J., Zheng, D., Wei, N. et al. A New Quassinoid from Brucea javanica. Chem Nat Compd 58, 650–652 (2022). https://doi.org/10.1007/s10600-022-03762-2
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DOI: https://doi.org/10.1007/s10600-022-03762-2