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Cadabatone, a New Sesquiterpene Lactone from Cadaba fruticosa

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Chemistry of Natural Compounds Aims and scope

Cadabatone (1), a new eudesmanolide-type sesquiterpene lactone, has been isolated from the EtOAc soluble subfraction of the methanolic extract of Cadaba fruticosa (L.) Druce, along with known compounds, 3-epierivanin (2), 3,5,7,4-tetrahydroxyflavone (3), esculetin (4), rosmarinic acid (5), α-amyrin (6), and β-amyrin (7), isolated for the first time from this species. The structures of these compounds were elucidated by spectroscopic studies including MS, IR, 1D and 2D NMR spectroscopy.

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Authors and Affiliations

  1. Department of Applied Chemistry, University of Karachi, Karachi, 75270, Pakistan

    Ayesha Abdul Jabbar, Sadia Khan, Mehdi Hassan Kazmi & Farah Inamullah

  2. International Centre for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan

    Abdul Malik & Itrat Fatima

  3. Pharmaceutical Research Centre, PCSIR Laboratories Complex Karachi, Karachi, 75270, Pakistan

    Sadia Farheen & Beena Naqvi

Authors
  1. Ayesha Abdul Jabbar
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  2. Sadia Khan
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  3. Mehdi Hassan Kazmi
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  4. Abdul Malik
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  5. Itrat Fatima
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  6. Farah Inamullah
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  7. Sadia Farheen
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  8. Beena Naqvi
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Correspondence to Abdul Malik.

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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2023, pp. 236–238

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Jabbar, A.A., Khan, S., Kazmi, M.H. et al. Cadabatone, a New Sesquiterpene Lactone from Cadaba fruticosa. Chem Nat Compd 59, 278–281 (2023). https://doi.org/10.1007/s10600-023-03976-y

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  • DOI: https://doi.org/10.1007/s10600-023-03976-y

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