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Synthesis and antioxidant activity of some new N-alkylated pyrazole-containing benzimidazoles

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Chemistry of Heterocyclic Compounds Aims and scope

A series of new N-substituted pyrazole-containing benzimidazoles was synthesized starting from 1,2-diaminobenzene and pyrazole-4-carbaldehyde in good yield. Antioxidant activity of all title compounds was assessed using 2,2-diphenyl-1-picrylhydrazyl and hydrogen peroxide assays. Some of the synthesized compounds having benzyl substituent at the imidazole nitrogen exhibited good activity in both assays.

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The authors thank Council of Scientific and Industrial Research (CSIR), New Delhi, INDIA for providing financial assistance (S. No. 02(0137)/13/EMR-II, dated 12-04-2013).

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Authors and Affiliations

  1. Sri Venkateswara University, University Ave., Tirupati, 517 502, India

    Mahesh Bellam, Mohan Gundluru, Santhisudha Sarva, Vasudeva Reddy Netala, Vijaya Tartte & Suresh Reddy Cirandur

  2. Sri Padmavathi Women’s Degree & P.G. College, University Ave., Tirupati, 517 502, India

    Sridevi Chadive

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  1. Mahesh Bellam
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  2. Mohan Gundluru
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  3. Santhisudha Sarva
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  4. Sridevi Chadive
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  5. Vasudeva Reddy Netala
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  6. Vijaya Tartte
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  7. Suresh Reddy Cirandur
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Correspondence to Suresh Reddy Cirandur.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(2), 173–178

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Bellam, M., Gundluru, M., Sarva, S. et al. Synthesis and antioxidant activity of some new N-alkylated pyrazole-containing benzimidazoles. Chem Heterocycl Comp 53, 173–178 (2017). https://doi.org/10.1007/s10593-017-2036-6

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  • DOI: https://doi.org/10.1007/s10593-017-2036-6

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