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Isoxazolo[4,3-e]indazole as a new heterocyclic system: design, synthesis, spectroscopic characterization, and antibacterial activity

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Chemistry of Heterocyclic Compounds Aims and scope

The new heterocyclic system isoxazolo[4,3-e]indazole was synthesized via the nucleophilic substitution of a hydrogen in 1-methyl-5-nitro-1H-indazole with different aryl acetonitriles in basic medium. The fluorescence properties and antibacterial activities of the new compounds against Gram-positive and Gram-negative bacterial species were also studied.

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We would like to express our sincere gratitude to Mashhad Islamic Azad University for financial support of this work. We must also acknowledge Maryam Jajarmi (Khorasan Razavi Rural Water and Wastewater Co.) for her assistance in antibacterial studies.

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Authors and Affiliations

  1. Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, Iran

    Masoumeh Ghaemi & Mehdi Pordel

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  1. Masoumeh Ghaemi
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  2. Mehdi Pordel
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Correspondence to Mehdi Pordel.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(1), 52–57

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Ghaemi, M., Pordel, M. Isoxazolo[4,3-e]indazole as a new heterocyclic system: design, synthesis, spectroscopic characterization, and antibacterial activity. Chem Heterocycl Comp 52, 52–57 (2016). https://doi.org/10.1007/s10593-016-1833-7

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