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Acute dystonia following epileptic seizure after bupropion intoxication

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Abstract

Bupropion is an effective treatment for major depressive disorder and smoking cessation. In this paper, we present a case report about dystonia in the head and the neck after epileptic seizures due to 4200 mg of extended-release bupropion intake, and we aim to take attention to the rare neuropsychiatric side effects that may occur after the use of high doses of bupropion.

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Change history

  • 26 March 2021

    Some part in the body text and references of the article re-translated to Turkish.

Referanslar

  1. Costa R, Oliveira NG, Dinis-Oliveira RJ (2019) Pharmacokinetic and pharmacodynamic of bupropion: integrative overview of relevant clinical and forensic aspects. Drug Metab Rev 51(3):293–313

  2. Wang H-Y, Chou W-J, Huang T-Y, Hung C-F (2007) Acute dystonia resulting from abrupt bupropion discontinuation. Prog Neuropsychopharmacol Biol Psychiatry 31(3):766–768

  3. Wasif N, Wasif K, Saif MW (2017) Bupropion-induced acute dystonia with dose escalation and use of Naranjo nomogram. Cureus 9(4):e1157

  4. Elyasi F, Mahtiyan E (2016) Acute dystonia after single dose of bupropion. Indian J Psychol Med. 38(5):460–462

  5. Demir S, Atli A, Gunes M, Cati S, Akil E, Cetinkaya N (2015) Single dose bupropion related acute dystonia: a case report. Anadolu Psikiyatri Derg 16(3):227–230

  6. Cheng W-C, Liu C-M, Hsieh MH, Hwang T-J (2009) Bupropion-related parkinsonism and dystonia. J Clin Psychopharmacol 29(6):616–618

  7. Milton JC, Abdulla A (2007) Prolonged oro-facial dystonia in a 58 year old female following therapy with bupropion and St John’s Wort. Br J Clin Pharmacol 64(5):717–718

    Article  Google Scholar 

  8. Detweiler MB, Harpold GJ (2002) Bupropion-induced acute dystonia. Ann Pharmacother 36(2):251–254

  9. Elhusseiny AM, Grush A, Dagi LR (2020) Acute, severe dystonia after strabismus surgery in a patient on propofol, ondansetron, and bupropion. Journal of American Association for Pediatric Ophthalmology and Strabismus 24(5):312–314

  10. Ozen B, Gunal DI, Turkmen C, Agan K, Elmaci NT (2011) Speech-induced primary lingual dystonia: a rare focal dystonia. Neurol Sci 32(1):155–157

  11. Downs AM, Roman KM, Campbell SA, Pisani A, Hess EJ, Bonsi P (2019) The neurobiological basis for novel experimental therapeutics in dystonia. Neurobiol Dis 130:104526

    Article  CAS  Google Scholar 

  12. Di Biasio F, Baldi O, Avanzino L, Marchese R. Segmental dystonia after radical neck dissection and radiotherapy: a case report. Neurol Sci. 2020:1–2

  13. Hawthorne JM, Caley CF (2015) Extrapyramidal reactions associated with serotonergic antidepressants. Ann Pharmacother 49(10):1136–1152

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Authors and Affiliations

  1. Psikiyatri Anabilim Dalı Tıp Fakültesi, Van Yüzüncü Yıl Üniversitesi, 65100, Van, Türkiye

    Faruk Kurhan

  2. Department of Psychiatry, Manisa Akhisar Mustafa Kirazoğlu State Hospital, Manisa, Turkey

    Gülsüm Zuhal Kamış

  3. Psikiyatri, Kliniği Florence Nightingale Hastanesi, İstanbul, Türkiye

    Emine füsun Akyüz Çim

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  1. Faruk Kurhan
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  2. Gülsüm Zuhal Kamış
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  3. Emine füsun Akyüz Çim
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Correspondence to Faruk Kurhan.

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Kurhan, F., Kamış, G.Z. & Çim, E.f.A. Acute dystonia following epileptic seizure after bupropion intoxication. Neurol Sci 42, 4381–4386 (2021). https://doi.org/10.1007/s10072-021-05139-9

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  • DOI: https://doi.org/10.1007/s10072-021-05139-9

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