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Anti-inflammatory and analgesic effects of two new flavone C-glycosides from Panzeria alaschanica

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Abstract

Two new flavone C-glycosides, named as panzeroside A and B were isolated from the n-BuOH crude extract of the aerial parts of Panzeria alaschanica Kuprian. Their structures were elucidated by spectroscopic methods, including UV, IR, ESI–MS, 1D NMR, and 2D NMR techniques. Anti-inflammatory and analgesic activities of were assessed in rats by the hot plate test, paw pressure, and carrageenan-induced paw oedema. The two new compounds showed significant and dose-dependent analgesic and anti-inflammatory effects.

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Acknowledgments

This work was supported by the scientific research project of the Inner Mongolia Autonomous Region colleges and Universities in China (No. NJZZ14182) and the project of collaborative innovation center of Jiangxi triditional medicine (JXXT201402003).

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Authors and Affiliations

  1. College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao, 028000, Inner Mongolia, China

    Qinghu Wang, Jiesi Wu, Xiaolan Wu, Wenquan Tai, Nayintai Dai, Rongjun Wu & Narenchaoketu Han

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  1. Qinghu Wang
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  2. Jiesi Wu
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  3. Xiaolan Wu
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  4. Wenquan Tai
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Correspondence to Qinghu Wang.

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Wang, Q., Wu, J., Wu, X. et al. Anti-inflammatory and analgesic effects of two new flavone C-glycosides from Panzeria alaschanica . Monatsh Chem 146, 1025–1030 (2015). https://doi.org/10.1007/s00706-015-1414-y

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  • DOI: https://doi.org/10.1007/s00706-015-1414-y

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