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Design and synthesis of nano-iron oxyhydroxide-based molecularly imprinted electrochemical sensors for trace-level carbendazim detection in actual samples

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Abstract

Carbendazim (CBD) is widely used as a fungicide that acts as a pesticide in farming to prevent crop diseases. However, CBD can remain on crops for a long time. When consumed by humans and animals, it produces a range of toxic symptoms and poses a serious threat to their health. Therefore, the detection of CBD is necessary. Traditional assay strategies for CBD detection, although sensitive and practical, can hardly achieve fast, robust monitoring during food processing and daily life. Here, we designed a novel electrochemical sensor for CBD detection. In this method, iron oxyhydroxide nanomaterial (β-FeOOH) was first prepared by hydrothermal method. Then, a molecularly imprinted polymer (MIP) layer was electropolymerized on the surface using CBD as the template and resorcinol (RC) as the functional monomer. The synergistic interaction between β-FeOOH and MIP endows the MIP/β-FeOOH/CC-based electrochemical sensor with high specificity and sensitivity. Under optimal conditions, the MIP/β-FeOOH/CC-based sensor showed a wide linear range of 39 pM–80 nM for CBD and a detection limit as low as 25 pM. Therefore, the as-prepared sensor can be a practical and effective tool for pesticide residue detection.

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Acknowledgements

The authors thank Dr. Chao Wang of the Department of Chemistry and Chemical Engineering (SUST) for helpful advice and discussion.

Funding

This work was financially supported by the General Project of Shaanxi Province Research and Development Key Program (No. 2022NY-042), Xi’an Science and Technology Planning Project–Scientific and Technological Personnel Service Enterprise Project (No. 22GXFW0012), Xi’an Key Laboratory of Advanced Performance Materials and Polymer (No. 2021122), Science and Technology Plan Project by Shaanxi Provincial Education Department (No. 21JP114) and District of Shaanxi Province Project (No. 202129), Science Technology Department of Shaanxi province (No. 2022PT-44), and the Scientific Research Program Funded by the Shaanxi Provincial Education Department (21JP114).

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Shaanxi University of Science & Technology, Xi’an, 710021, China

    Dong Yang, Xuhua Li, Xiangyu Li, Jifan Chen, Ting Zhang & Haihua Wang

  2. Xi’an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science & Technology, Xi’an, 710021, China

    Dong Yang, Xuhua Li, Xiangyu Li, Jifan Chen, Ting Zhang & Haihua Wang

  3. Key Laboratory of Chemical Additives for China National Light Industry, Xi’an, 710021, China

    Dong Yang, Xuhua Li, Xiangyu Li, Jifan Chen, Ting Zhang & Haihua Wang

  4. School of Clinical Medicine, Xi’an Medical University, Xi’an, 710021, China

    Ting Lian

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  1. Dong Yang
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  2. Xuhua Li
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  3. Xiangyu Li
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Correspondence to Dong Yang or Haihua Wang.

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Yang, D., Li, X., Li, X. et al. Design and synthesis of nano-iron oxyhydroxide-based molecularly imprinted electrochemical sensors for trace-level carbendazim detection in actual samples. Microchim Acta 191, 163 (2024). https://doi.org/10.1007/s00604-024-06236-0

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