Abstract
2- and 4-substituted 5-fluoropyrimidines were synthesized by the reaction of 2,4-dichloro-5-fluoropyrimidine with alkoxides, phenols, and aromatic and heterocyclic amines.
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C. Hennart and E. Merlin, Bull. Soc. Chim. France, 741 (1959).
L. D. Protsenko and Yu. I. Bogodist, Zh. Obshch. Khim., 33, 537 (1963).
E. Profft and H. Raddatz, Arch. Pharm., 295, 649 (1962).
T. Mattsukawa and K. Shirakawa, J. Pharm. Soc. Japan, 71, 1313 (1951).
D. Ghosh and M. Mukherjee, J. Med. Chem., 11, 1237 (1968).
R. A. Paégle, M. G. Plata, and M. Yu. Lidak, Khim. Geterotsikl. Soedin., 475 (1966).
Yu. I. Bogodist and L. D. Protsenko, Ukr. Khim. Zh., 36, 1142 (1970).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 117–119, January, 1973.
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Kuz'menko, I.I., Protsenko, L.D. 2- and 4-substituted 5-fluoropyrimidines. Chem Heterocycl Compd 9, 105–107 (1973). https://doi.org/10.1007/BF00476164
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DOI: https://doi.org/10.1007/BF00476164