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The Cellular and Molecular Mechanisms of Ovarian Aging

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Ovarian Aging

Abstract

The initial primordial follicle pool size and the activation and depletion rates determine fertility potential. Generally, primordial follicles have three states: resting, growth, and atresia/degeneration. Over-activation and abnormal atresia of primordial follicles are leading causes of ovarian aging [1]. Therefore, this section focuses on the molecular mechanisms of primordial follicle activation (PFA) and follicular atresia.

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  1. Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Tong Wu, Fangfang Fu, Xiang Li, Su Zhou, Yueyue Xi, Meng Wu & Dingfu Du

  2. Department of Obstetrics and Gynecology, Zhongnan hospital of Wuhan University, Wuhan, China

    Jing Cheng

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Wu, T. et al. (2023). The Cellular and Molecular Mechanisms of Ovarian Aging. In: Wang, S. (eds) Ovarian Aging. Springer, Singapore. https://doi.org/10.1007/978-981-19-8848-6_5

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