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Aquaporins in Immune System

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Aquaporins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1398))

Abstract

Recent studies have shown that at least six aquaporins (AQPs), including AQP1, AQP3, AQP4, AQP5, AQP7, and AQP9, are expressed in immune system. These AQPs distribute in lymphocytes, macrophages, dendritic cells, and neutrophils, and mediate water and glycerol transportation in these cells, which play important roles in innate and adaptive immune functions. Immune system plays important roles in body physiological functions and health. Therefore, understanding the association between AQPs and immune system may provide approaches to prevent and treat related diseases. Here we will discuss the expression and physiological functions of AQPs in immune system and summarize recent researches on AQPs in immune diseases.

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Acknowledgments

The work was supported by the National Natural Science Foundation of China grants 81974083, 82273999, 81620108029, 81330074 and the Beijing Natural Science Foundation grant 7212151.

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Authors and Affiliations

  1. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China

    Yazhu Quan

  2. Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China

    Yazhu Quan

  3. Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China

    Yazhu Quan

  4. Department of Clinical Laboratory, The Second Hospital of Jilin University, Changchun, Jilin, China

    Bo Kan

  5. School of Basic Medical Sciences, Peking University, Beijing, China

    Baoxue Yang

Authors
  1. Yazhu Quan
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  2. Bo Kan
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  3. Baoxue Yang
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Correspondence to Baoxue Yang .

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Editors and Affiliations

  1. School of Basic Medical Sciences, Peking University, Beijing, China

    Baoxue Yang

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© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Quan, Y., Kan, B., Yang, B. (2023). Aquaporins in Immune System. In: Yang, B. (eds) Aquaporins. Advances in Experimental Medicine and Biology, vol 1398. Springer, Singapore. https://doi.org/10.1007/978-981-19-7415-1_13

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