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Application of Nanobiosensor in Health Care Sector

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Bio-Nano Interface

Abstract

Nanotechnology is expected to have a revolutionary effect on biology and medicine. It has been able to provide special perspectives to the probe and control a variety of biological along with medical processes that take place at nanometer scales. Nanoparticles offer some advantages like sensing, image enhancement, and delivery agents. These are the approaches for exploiting nanotechnology in medicine as well as in the health care sector. Nanobiosensors are nano-scaled quantifiable devices, those involve nano-conjugated biological particulars as a transducing system to detect the minute quanta of any physical, chemical, or biological analytes. The appearance of nanobiosensors has actually developed the detection of many disorders like cancer, allergic responses, diabetes, and many other diseases and malfunctions related to these diseases. The present review comprehensively scrutinizes various types of cancer detection biosensors fabricated so far along with their technical evaluation regarding the potency and efficiency of selected bioreceptors biotransducers. For the diagnosis as well as monitoring of prostate cancer, the prostate-specific antigen (PSA) has been identified and considered as the most valid clinical tool. By using amperometric immunosensor, prostate cancer can be monitored. For lung cancer detection a new rapid, as well as sensitive technique for screening, is required. With this approach, for the identification of many major disease biomarkers through sensitive, easy as well as rapid applications, biosensors have provided a promising technology as diagnostics tools. In this paper we discuss about lung cancer, prostate cancer, brain cancer, breast cancer, and pancreatic cancer. Also, current disease diagnostics techniques, protein and genetic biomarkers of diseases, as well as emerging biosensor technology for quick identification, are discussed. Moreover, the use of different nanomaterials in various forms as components of biosensors for the detection of various human pathogens has been further explored.

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Authors and Affiliations

  1. Centre for Biotechnology, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

    Subham Preetam, Lipsa Dash, Suman Sudha Sarangi, Mitali Madhusmita Sahoo & Arun Kumar Pradhan

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  1. Subham Preetam
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  2. Lipsa Dash
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  4. Mitali Madhusmita Sahoo
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  5. Arun Kumar Pradhan
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Correspondence to Arun Kumar Pradhan .

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Editors and Affiliations

  1. Centre for Biotechnology, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

    Manoranjan Arakha

  2. Centre for Biotechnology, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

    Arun Kumar Pradhan

  3. Department of Life Science, National Institute of Technology Rourkela, Rourkela, Odisha, India

    Suman Jha

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© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Preetam, S., Dash, L., Sarangi, S.S., Sahoo, M.M., Pradhan, A.K. (2022). Application of Nanobiosensor in Health Care Sector. In: Arakha, M., Pradhan, A.K., Jha, S. (eds) Bio-Nano Interface. Springer, Singapore. https://doi.org/10.1007/978-981-16-2516-9_14

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