Skip to main content
SpringerLink
Log in

Biliary Radio Frequency Ablation (RFA)

  • Chapter
  • First Online:
Innovations in Gastrointestinal Endoscopy

  • 339 Accesses

Abstract

Radiofrequency ablation (RFA) is a well-established ablative procedure that causes coagulative necrosis of tumors, leading to local destruction of many solid-organ malignancies. RFA also has been known as a palliative method for the endoscopic treatment of malignant bile duct obstruction. Novel RFA catheters have opened the possibility of new endoscopic treatments and have been successfully used in endoscopic approaches for palliative intraductal ablation in patients with malignant bile duct obstruction. In this chapter, we reviewed the detailed methods and outcomes of endobiliary RFA.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Goldberg SN. Radiofrequency tumor ablation: principles and techniques. Eur J Ultrasound. 2001;13:129–47.

    Article  CAS  Google Scholar 

  2. Song TJ, Seo DW, Lakhtakia S, et al. Initial experience of EUS-guided radiofrequency ablation of unresectable pancreatic cancer. Gastrointest Endosc. 2016;83:440–3.

    Article  Google Scholar 

  3. McCarty TR, Rustagi T. New indications for endoscopic radiofrequency ablation. Clin Gastroenterol Hepatol. 2018;16:1007–17.

    Article  Google Scholar 

  4. Larghi A, Rimbas M, Tringali A, et al. Endoscopic radiofrequency biliary ablation treatment: a comprehensive review. Dig Endosc. 2019;31(3):245–55. https://doi.org/10.1111/den.13298.

    Article  PubMed  Google Scholar 

  5. Schueller G, Kettenbach J, Sedivy R, et al. Heat shock protein expression induced by percutaneous radiofrequency ablation of hepatocellular carcinoma in vivo. Int J Oncol. 2004;24:609–13.

    CAS  PubMed  Google Scholar 

  6. Haen SP, Pereira PL, Salih HR, et al. More than just tumor destruction: immunomodulation by thermal ablation of cancer. Clin Dev Immunol. 2011;2011:160250.

    Article  Google Scholar 

  7. Mao EJ, Watson JB, Soares G, et al. Successful percutaneous endobiliary radiofrequency ablation for unresectable malignant biliary obstruction: a case report and review of the literature. J Gastrointest Cancer. 2014;45(Suppl 1):55–7.

    Article  CAS  Google Scholar 

  8. Itoi T, Isayama H, Sofuni A, et al. Evaluation of effects of a novel endoscopically applied radiofrequency ablation biliary catheter using an ex-vivo pig liver. J Hepatobiliary Pancreat Sci. 2012;19:543–7.

    Article  Google Scholar 

  9. Rhim H, Goldberg SN, Dodd GD 3rd, et al. Essential techniques for successful radio-frequency thermal ablation of malignant hepatic tumors. Radiographics. 2001;21 Spec No:S17–35; discussion S6–9.

    Article  CAS  Google Scholar 

  10. Rustagi T, Jamidar PA. Intraductal radiofrequency ablation for management of malignant biliary obstruction. Dig Dis Sci. 2014;59:2635–41.

    Article  Google Scholar 

  11. Cho JH, Lee KH, Kim JM, et al. Safety and effectiveness of endobiliary radiofrequency ablation according to the different power and target temperature in a swine model. J Gastroenterol Hepatol. 2017;32:521–6.

    Article  Google Scholar 

  12. Loew BJ, Howell DA, Sanders MK, et al. Comparative performance of uncoated, self-expanding metal biliary stents of different designs in 2 diameters: final results of an international multicenter, randomized, controlled trial. Gastrointest Endosc. 2009;70:445–53.

    Article  Google Scholar 

  13. Hong W, Sun X, Zhu Q. Endoscopic stenting for malignant hilar biliary obstruction: should it be metal or plastic and unilateral or bilateral? Eur J Gastroenterol Hepatol. 2013;25:1105–12.

    Article  Google Scholar 

  14. Kaassis M, Boyer J, Dumas R, et al. Plastic or metal stents for malignant stricture of the common bile duct? Results of a randomized prospective study. Gastrointest Endosc. 2003;57:178–82.

    Article  Google Scholar 

  15. Alis H, Sengoz C, Gonenc M, et al. Endobiliary radiofrequency ablation for malignant biliary obstruction. Hepatobiliary Pancreat Dis Int. 2013;12:423–7.

    Article  Google Scholar 

  16. Figueroa-Barojas P, Bakhru MR, Habib NA, et al. Safety and efficacy of radiofrequency ablation in the management of unresectable bile duct and pancreatic cancer: a novel palliation technique. J Oncol. 2013;2013:910897.

    Article  Google Scholar 

  17. Sharaiha RZ, Natov N, Glockenberg KS, et al. Comparison of metal stenting with radiofrequency ablation versus stenting alone for treating malignant biliary strictures: is there an added benefit? Dig Dis Sci. 2014;59:3099–102.

    Article  CAS  Google Scholar 

  18. Sharaiha RZ, Sethi A, Weaver KR, et al. Impact of radiofrequency ablation on malignant biliary strictures: results of a collaborative registry. Dig Dis Sci. 2015;60:2164–9.

    Article  Google Scholar 

  19. Kallis Y, Phillips N, Steel A, et al. Analysis of endoscopic radiofrequency ablation of biliary malignant strictures in pancreatic Cancer suggests potential survival benefit. Dig Dis Sci. 2015;60:3449–55.

    Article  CAS  Google Scholar 

  20. Laleman W, van der Merwe S, Verbeke L, et al. A new intraductal radiofrequency ablation device for inoperable biliopancreatic tumors complicated by obstructive jaundice: the IGNITE-1 study. Endoscopy. 2017;49:977–82.

    Article  Google Scholar 

  21. Strand DS, Cosgrove ND, Patrie JT, et al. ERCP-directed radiofrequency ablation and photodynamic therapy are associated with comparable survival in the treatment of unresectable cholangiocarcinoma. Gastrointest Endosc. 2014;80:794–804.

    Article  Google Scholar 

  22. Schmidt A, Bloechinger M, Weber A, et al. Short-term effects and adverse events of endoscopically applied radiofrequency ablation appear to be comparable with photodynamic therapy in hilar cholangiocarcinoma. United European Gastroenterol J. 2016;4:570–9.

    Article  CAS  Google Scholar 

  23. Yang J, Wang J, Zhou H, et al. Efficacy and safety of endoscopic radiofrequency ablation for unresectable extrahepatic cholangiocarcinoma: a randomized trial. Endoscopy. 2018;50:751–60.

    Article  Google Scholar 

  24. Sofi AA, Khan MA, Das A, et al. Radiofrequency ablation combined with biliary stent placement versus stent placement alone for malignant biliary strictures: a systematic review and meta-analysis. Gastrointest Endosc. 2018;87:944–51.e1.

    Article  Google Scholar 

  25. Acu B, Kurtulus OE. Feasibility and safety of percutaneous transhepatic endobiliary radiofrequency ablation as an adjunct to biliary stenting in malignant biliary obstruction. Diagn Interv Imaging. 2018;99:237–45.

    Article  CAS  Google Scholar 

  26. Inoue T, Ito K, Yoneda M. Antegrade radiofrequency ablation and stenting for biliary stricture through endoscopic ultrasound-guided hepaticogastrostomy. Dig Endosc. 2018;30:793–4.

    Article  Google Scholar 

  27. Inoue T, Ito K, Yoneda M. Radiofrequency ablation combined with multiple biliary metal stent placement using short-type single-balloon endoscope in patients with surgically altered anatomy. Dig Endosc. 2018;30:395–6.

    Article  Google Scholar 

  28. Valente R, Urban O, Del Chiaro M, et al. ERCP-directed radiofrequency ablation of ampullary adenomas: a knife-sparing alternative in patients unfit for surgery. Endoscopy. 2015;47(Suppl 1 UCTN):E515–6.

    PubMed  Google Scholar 

  29. Mehendiratta V, Desilets DJ. Use of radiofrequency ablation probe for eradication of residual adenoma after ampullectomy. Gastrointest Endosc. 2015;81:1055–6.

    Article  Google Scholar 

  30. Rustagi T, Irani S, Reddy DN, et al. Radiofrequency ablation for intraductal extension of ampullary neoplasms. Gastrointest Endosc. 2017;86:170–6.

    Article  Google Scholar 

  31. Camus M, Napoleon B, Vienne A, et al. Efficacy and safety of endobiliary radiofrequency ablation for the eradication of residual neoplasia after endoscopic papillectomy: a multicenter prospective study. Gastrointest Endosc. 2018;88:511–8.

    Article  Google Scholar 

  32. Nayar MK, Oppong KW, Bekkali NLH, et al. Novel temperature-controlled RFA probe for treatment of blocked metal biliary stents in patients with pancreaticobiliary cancers: initial experience. Endosc Int Open. 2018;6:E513–E7.

    Article  Google Scholar 

  33. Yoon WJ, Kim YT, Daglilar ES, et al. Evaluation of bipolar radiofrequency ablation for occluded self-expandable metal stents in the bile duct: in vivo and in vitro study. Endoscopy. 2015;47:1167–70.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

    Tae Jun Song & Dong Wan Seo

Authors
  1. Tae Jun Song
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dong Wan Seo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Dong Wan Seo .

Editor information

Editors and Affiliations

  1. Division of Gastroenterology and Hepatology, University of Kansas School of Medicine, VA Medical Center, Kansas City, MO, USA

    Prateek Sharma

  2. Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Andhra Pradesh, India

    Nageshwar Reddy

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Song, T.J., Seo, D.W. (2021). Biliary Radio Frequency Ablation (RFA). In: Sharma, P., Reddy, N. (eds) Innovations in Gastrointestinal Endoscopy. Springer, Singapore. https://doi.org/10.1007/978-981-15-9247-8_8

Download citation

  • DOI: https://doi.org/10.1007/978-981-15-9247-8_8

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-9246-1

  • Online ISBN: 978-981-15-9247-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation