Skip to main content

Diaphragm EMG Recording and Its Application in Sleep Medicine

  • Chapter
  • First Online:
Sleep and its Disorders

Part of the book series: Translational Medicine Research ((TRAMERE))

Abstract

Pathophysiological changes in obstructive sleep apnea (OSA) related to neural respiratory drive can be assessed by diaphragm EMG recorded from surface electrodes, in particular, esophageal electrode. Although esophageal pressure was considered to be the gold standard in assessment of respiratory effort, it can be influenced by changes in lung volume and airflow. Diaphragm EMG recorded from esophageal electrode has an advantage over esophageal pressure in assessment of neural respiratory drive in patients with obstructive sleep apnea whose airflow and lung volume are not stable during overnight sleep. In this chapter, the recording of diaphragm EMG from an esophageal electrode catheter is discussed. Application of diaphragm EMG has been used to further understand the mechanism of pathophysiological changes in patients with OSA including those with both OSA and chronic obstructive pulmonary disease (COPD), overlap syndrome. Assessment of diaphragm EMG can also be used to differentiate central from obstructive sleep apneas.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • American Thoracic Society/European Respiratory Society. ATS/ERS statement on respiratory muscle testing. Am J Respir Crit Care Med. 2002;166(4):518–624.

    Article  Google Scholar 

  • Chaouat A, Weitzenblum E, Krieger J, Ifoundza T, Oswald M, Kessler R. Association of chronic obstructive pulmonary disease and sleep apnea syndrome. Am J Respir Crit Care Med. 1995;151(1):82–6.

    Article  CAS  Google Scholar 

  • Du W, Liu J, Zhou J, Ye D, OuYang Y, Deng Q. Obstructive sleep apnea, COPD, the overlap syndrome, and mortality: results from the 2005–2008 National Health and Nutrition Examination Survey. Int J Chron Obstruct Pulmon Dis. 2018;13:665–74.

    Article  Google Scholar 

  • Gleeson K, Zwillich CW, White DP. The influence of increasing ventilatory effort on arousal from sleep. Am Rev Respir Dis. 1990;142(2):295–300.

    Article  CAS  Google Scholar 

  • He BT, Lu G, Xiao SC, Chen R, Steier J, Moxham J, et al. Coexistence of OSA may compensate for sleep related reduction in neural respiratory drive in patients with COPD. Thorax. 2017;72(3):256–62.

    Article  Google Scholar 

  • Kay A, Trinder J, Kim Y. Individual differences in relationship between upper airway resistance and ventilation during sleep onset. J Appl Physiol (1985). 1995;79(2):411–9.

    Article  CAS  Google Scholar 

  • Kimoff RJ, Cheong TH, Olha AE, Charbonneau M, Levy RD, Cosio MG, et al. Mechanisms of apnea termination in obstructive sleep apnea. Role of chemoreceptor and mechanoreceptor stimuli. Am J Respir Crit Care Med. 1994;149(3 Pt 1):707–14.

    Article  CAS  Google Scholar 

  • Laveneziana P, Albuquerque A, Aliverti A, Babb T, Barreiro E, Dres M, et al. ERS statement on respiratory muscle testing at rest and during exercise. Eur Respir J. 2019;53(6):1801214.

    Article  Google Scholar 

  • Luo YM, Moxham J. Measurement of neural respiratory drive in patients with COPD. Respir Physiol Neurobiol. 2005;146(2–3):165–74.

    Article  CAS  Google Scholar 

  • Luo YM, Polkey MI, Johnson LC, Lyall RA, Harris ML, Green M, et al. Diaphragm EMG measured by cervical magnetic and electrical phrenic nerve stimulation. J Appl Physiol (1985). 1998;85(6):2089–99.

    Article  CAS  Google Scholar 

  • Luo YM, Lyall RA, Lou Harris M, Rafferty GF, Polkey MI, Moxham J. Quantification of the esophageal diaphragm electromyogram with magnetic phrenic nerve stimulation. Am J Respir Crit Care Med. 1999;160(5 Pt 1):1629–34.

    Article  CAS  Google Scholar 

  • Luo YM, Moxham J, Polkey MI. Diaphragm electromyography using an oesophageal catheter: current concepts. Clin Sci. 2008a;115(8):233–44.

    Article  Google Scholar 

  • Luo YM, Wu HD, Tang J, Jolley C, Steier J, Moxham J, et al. Neural respiratory drive during apnoeic events in obstructive sleep apnoea. Eur Respir J. 2008b;31(3):650–7.

    Article  CAS  Google Scholar 

  • Luo YM, Tang J, Jolley C, Steier J, Zhong NS, Moxham J, et al. Distinguishing obstructive from central sleep apnea events: diaphragm electromyogram and esophageal pressure compared. Chest. 2009;135(5):1133–41.

    Article  Google Scholar 

  • Luo YM, Li RF, Jolley C, Wu HD, Steier J, Moxham J, et al. Neural respiratory drive in patients with COPD during exercise tests. Respiration. 2011;81(4):294–301.

    Article  CAS  Google Scholar 

  • Luo YM, He BT, Wu YX, Yuan H, Xu J, Moxham J, et al. Neural respiratory drive and ventilation in patients with chronic obstructive pulmonary disease during sleep. Am J Respir Crit Care Med. 2014;190(2):227–9.

    Article  Google Scholar 

  • Marin JM, Soriano JB, Carrizo SJ, Boldova A, Celli BR. Outcomes in patients with chronic obstructive pulmonary disease and obstructive sleep apnea: the overlap syndrome. Am J Respir Crit Care Med. 2010;182(3):325–31.

    Article  Google Scholar 

  • Morrell MJ, Harty HR, Adams L, Guz A. Breathing during wakefulness and NREM sleep in humans without an upper airway. J Appl Physiol (1985). 1996;81(1):274–81.

    Article  CAS  Google Scholar 

  • Patout M, Ramsay M, Mackie M, Lhuillier E, Grey N, Arbane G, et al. Home mechanical ventilation (HMV): setup and outcome in Europe. Eur Respir J. 2015;46:OA4780.

    Google Scholar 

  • Sanders MH, Newman AB, Haggerty CL, Redline S, Lebowitz M, Samet J, et al. Sleep and sleep-disordered breathing in adults with predominantly mild obstructive airway disease. Am J Respir Crit Care Med. 2003;167(1):7–14.

    Article  Google Scholar 

  • Sinderby C, Spahija J, Beck J, Kaminski D, Yan S, Comtois N, et al. Diaphragm activation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001;163(7):1637–41.

    Article  CAS  Google Scholar 

  • Soler X, Gaio E, Powell FL, Ramsdell JW, Loredo JS, Malhotra A, et al. High prevalence of obstructive sleep apnea in patients with moderate to severe chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2015;12(8):1219–25.

    PubMed  PubMed Central  Google Scholar 

  • Stoohs RA, Blum HC, Knaack L, Butsch-von-der-Heydt B, Guilleminault C. Comparison of pleural pressure and transcutaneous diaphragmatic electromyogram in obstructive sleep apnea syndrome. Sleep. 2005;28(3):321–9.

    PubMed  Google Scholar 

  • Xiao SC, Lu YR, Guo HX, Qiu ZH, Luo YM. Effect of expiratory load on neural inspiratory drive. Chin Med J. 2012;125(20):3629–34.

    CAS  PubMed  Google Scholar 

  • Xiao SC, He BT, Steier J, Moxham J, Polkey MI, Luo YM. Neural respiratory drive and arousal in patients with obstructive sleep apnea hypopnea. Sleep. 2015;38(6):941–9.

    PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yuan-Ming Luo .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature B.V. and Shanghai Jiao Tong University Press

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Luo, YM., Luo, YM. (2022). Diaphragm EMG Recording and Its Application in Sleep Medicine. In: Pack, A.I., Li, Q.Y. (eds) Sleep and its Disorders. Translational Medicine Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-2168-2_9

Download citation

Publish with us

Policies and ethics