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Phytochemistry and Pharmacological Studies of Indian Cinnamomum Schaeff

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Bioprospecting of Tropical Medicinal Plants

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Abstract

The genus Cinnamomum belongs to the Lauraceae family consisting of evergreen shrubs and trees, and many are aromatic. Over 250 species of Cinnamomum are reported all over the world and distributed in tropical and subtropical regions of North America, South America, Central America, Oceania, Asia, and Australia. In India, about 45 species have been reported along with 31 endemic species. They are being cultivated as landscape plants due to their enormous economic and medicinal value. This review systematically evaluated the documents available in the literature to date on phytochemistry and pharmacology of species of Cinnamomum from India. The data was obtained from scientific databases including Google Scholar, Scopus, PubMed, Elsevier, and ScienceDirect. Usually, the species of Cinnamomum are identified according to their fragrant and trinerved leaves, paniculate inflorescences, flower with nine stamens, and fruits seated on a cupule. Also this genus is a potential source of various secondary metabolites with interesting chemical structures and notable bioactivities. They have been included in food as spices and also found uses in traditional medicines. Several chemical constituents like terpenes, lignans, phenylpropanoids, flavonoids, coumarins, steroids, and aliphatic and aromatic compounds were reported from Cinnamomum. Cinnamomum oils have also been reported to contain cinnamic acid, cinnamaldehyde, cinnamate, etc. Pharmacological properties such as antimicrobial, antioxidant, anti-inflammatory, and anticancer properties were recorded by in vitro and in vivo experimentation procedures. As this review compiles, the chemical constituents and bioactivities will provide a potential lead for future drug design and provide a reference for further research in Cinnamomum.

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Acknowledgments

Authors gratefully acknowledged the Science and Engineering Research Board, Department of Science and Technology (SERB-DST), Government of India, for the financial support in their work (CRG/2019/001873).

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  1. Department of Biology, The Gandhigram Rural Institute (Deemed to be University), Dindigul, India

    Saranya Surendran & Raju Ramasubbu

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  1. Center for Studies in Stem Cells Cell Therapy and Toxicological Genetics (CeTroGen), Graduate Program in Health and Development in the Midwest RegionFaculty of Medicine (FAMED)Federal University of Mato Grosso do Sul (UFMS) Campo Grande, Cidade Universitária, Pioneiros, Mato Grosso do Sul, Brazil

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  2. Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Kunming, Yunnan, China

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  3. Department of Botany, NSS College Nemmara, Palakkad, Kerala, India

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Surendran, S., Ramasubbu, R. (2023). Phytochemistry and Pharmacological Studies of Indian Cinnamomum Schaeff. In: Arunachalam, K., Yang, X., Puthanpura Sasidharan, S. (eds) Bioprospecting of Tropical Medicinal Plants. Springer, Cham. https://doi.org/10.1007/978-3-031-28780-0_26

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