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Emerging Nanomaterials as Radio-Sensitizer in Radiotherapy

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Harnessing Materials for X-ray Based Cancer Therapy and Imaging

Part of the book series: Nanomedicine and Nanotoxicology ((NANOMED))

Abstract

Radiotherapy has been involved in treating 50% of the cancer patients in the world and is based on the direct energy deposition into tumor tissues. The major constraint in radiotherapy is the adverse effect of deposited energy on the surrounded healthy tissues. The improved radiotherapeutic tactics involve the use of novel nanoparticles as radio-sensitizers. The nanoparticles, due to their high biocompatibility and optical properties, provide the enhanced localized damaging effect with the radiations targeted on the tumor site. There are different nanomaterials which offered enormous potential as radio-sensitizer and showed enhanced response with radiotherapy. In this chapter, we have discussed radio-sensitizing mechanisms and then different emerging nanomaterials being used as radio-sensitizer agents in radiotherapy.

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Author information

Authors and Affiliations

  1. Magnetic Materials Laboratory, Department of Physics, University of Agriculture, Faisalabad, Pakistan

    Ifrah Kiran, Yasir Javed, Mehwish Hanif & Riffat Ali

  2. National Institute of Biotechnology and Genetic Engineering, Government College University, Jhang Road, Faisalabad, Pakistan

    Naveed Akhtar Shad & Muhammad Sarwar

  3. Henan Key Laboratory of Photovoltaic Materials, School of Physics, Henan Normal University, Xinxiang, 453007, China

    Muhammad Munir Sajid

  4. University of Central Punjab, Faisalabad campus, Faisalabad, Pakistan

    Hafiz Zeeshan Mahmood

  5. ERNAM—Nanotechnology Research and Application Center, Erciyes University, Kayseri, 38039, Turkey

    Hamed Nosrati

  6. Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran

    Hamed Nosrati & Hossein Danafar

  7. Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine

    Hamed Nosrati & Hossein Danafar

  8. Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Baku, Azerbaijan

    Hamed Nosrati & Hossein Danafar

  9. Department of Physics, Central University of Punjab, Bathinda, 151401, India

    Surender K. Sharma

  10. Department of Physics, Federal University of Maranhao, Sao Luis, MA, 65080-805, Brazil

    Surender K. Sharma

Authors
  1. Ifrah Kiran
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  2. Naveed Akhtar Shad
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  3. Muhammad Munir Sajid
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  4. Hafiz Zeeshan Mahmood
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  5. Yasir Javed
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  6. Mehwish Hanif
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  7. Riffat Ali
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  8. Muhammad Sarwar
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  9. Hamed Nosrati
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  10. Hossein Danafar
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  11. Surender K. Sharma
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Corresponding authors

Correspondence to Naveed Akhtar Shad or Yasir Javed .

Editor information

Editors and Affiliations

  1. Central University of Punjab, Bathinda, India

    Surender Kumar Sharma

  2. Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran

    Hamed Nosrati

  3. John Paul II Catholic University of Lublin, Lublin, Poland

    Taras Kavetskyy

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Kiran, I. et al. (2022). Emerging Nanomaterials as Radio-Sensitizer in Radiotherapy. In: Sharma, S.K., Nosrati, H., Kavetskyy, T. (eds) Harnessing Materials for X-ray Based Cancer Therapy and Imaging. Nanomedicine and Nanotoxicology. Springer, Cham. https://doi.org/10.1007/978-3-031-04071-9_3

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