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Prediction and Prevention of Type 1 Diabetes

  • Chapter
Type 1 Diabetes

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

At present, the prediction of type 1 diabetes is not a major clinical issue outside of trials for diabetes prevention. Patients, especially children, usually present acutely with diabetes with a dramatic history of polyuria, polydipsia, and weight loss. Despite what in retrospect is almost always a clear-cut clinical history of diabetes, a significant number of children have a delay in diagnosis, which increases the risk of severe metabolic decompensation with diabetic ketoacidosis (DKA), cerebral edema, and death.

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Authors
  1. Aristides K. Maniatis MD
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  2. George S. Eisenbarth MD, PhD
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Editors and Affiliations

  1. Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Mark A. Sperling MD (Professor of Pediatrics and Chair Emeritus) (Professor of Pediatrics and Chair Emeritus)

  2. Division of Endocrinology, Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Mark A. Sperling MD (Professor of Pediatrics and Chair Emeritus) (Professor of Pediatrics and Chair Emeritus)

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Maniatis, A.K., Eisenbarth, G.S. (2003). Prediction and Prevention of Type 1 Diabetes. In: Sperling, M.A. (eds) Type 1 Diabetes. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-310-1_3

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