Type 1 Diabetes

Etiology and Treatment

  • Mark A. Sperling

Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Etiology

    1. Front Matter
      Pages 1-1
    2. Janice S. Dorman, Ronald E. LaPorte, Thomas J. Songer
      Pages 3-22
    3. Massimo Pietropaolo, Massimo Trucco
      Pages 23-54
    4. Aristides K. Maniatis, George S. Eisenbarth
      Pages 55-70
    5. Åke Lernmark, Choon Hee Chung
      Pages 71-92
    6. Tiinamaija Tuomi, Jaakko Perheentupa
      Pages 93-114
    7. Nicolai M. Doliba, Franz M. Matschinsky
      Pages 115-144
    8. Philip E. Cryer
      Pages 145-161
    9. Timothy G. Barrett
      Pages 163-179
  3. Treatment of Type 1 Diabetes

    1. Front Matter
      Pages 181-181
    2. Ram K. Menon, Mark A. Sperling
      Pages 183-198
    3. Baiju R. Shah, Bernard Zinman
      Pages 199-213
    4. Jean Betschart Roemer, Linda Siminerio
      Pages 249-260
    5. Christine A. Beebe
      Pages 261-276
  4. Special Management Issues in Type 1 Diabetes

    1. Front Matter
      Pages 277-277
    2. Nadia Tubiana-Rufi, Paul Czernichow
      Pages 279-292
    3. William V. Tamborlane, Elizabeth A. Boland, Margaret Grey
      Pages 293-305

About this book


The increasing incidence of diabetes worldwide has prompted a rapid growth in the pace of scientific discovery and clinical understanding of this enigmatic disease. In Type 1 Diabetes: Etiology and Treatment, well-recognized physicians and researchers review the latest thinking about the causes of this condition and the best approaches to treating both its acute and chronic complications. The treatment options discussed range from life-threatening diabetic ketoacidosis to contemporary insulin regimens, from open- and closed-loop insulin delivery devices to modern glucose-sensing mechanisms, as well as such daily life issues as nutrition and education. Also discussed are the management of children under the age of five, the special problems of preadolescents and adolescents, diabetic surgery, and pregnancy, along with the treatment and prevention of the long-term vascular complications that produce coronary artery disease, the loss of limbs, end-stage renal disease, and blindness. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.
Authoritative and up-to-date, Type 1 Diabetes: Etiology and Treatment provides all those caring for diabetic patients with a concise, accessible survey of today's best thinking about the causes, treatment, and management of this complex disease.


Diabetes Insulin Secretion Pancreas growth factor insulin metabolic control

Editors and affiliations

  • Mark A. Sperling
    • 1
    • 2
  1. 1.Department of PediatricsUniversity of Pittsburgh School of MedicinePittsburghUSA
  2. 2.Division of EndocrinologyChildren’s Hospital of PittsburghPittsburghUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59259-310-1
  • Copyright Information Humana Press 2003
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-61737-258-2
  • Online ISBN 978-1-59259-310-1
  • About this book