Summary
Total creatine kinase (CK), creatine kinase MB (CK-MB) and citrate synthase (CS) were determined in isolated and pooled type I and type II skeletal muscle fibres. Determinations were made on biopsies from 3 sedentary men, 3 junior cyclists and 2 elite cyclists.
CS and CK-MB activities were higher in the trained groups in both fibre types. The total CK activity was not related to training status, although it was lower in type I fibres than in type II fibres (p<0.05). The reverse relation was observed for CS and CK-MB activities (p<0.01). The ratio of type I/type II for CS was not related to training status, while the corresponding ratio for CK-MB increased with a greater degree of endurance training. For a given increase in CS activity, the increase in CK-MB activity was greater in type I fibres than in type II fibres (p<0.01). Thus, with endurance training there seems to be a specific adaptation for CK-MB, particularly in type I fibres.
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Jansson, E., Sylvén, C. Creatine kinase MB and citrate synthase in type I and type II muscle fibres in trained and untrained men. Europ. J. Appl. Physiol. 54, 207–209 (1985). https://doi.org/10.1007/BF02335931
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DOI: https://doi.org/10.1007/BF02335931