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Fused Deposition Modeling (FDM) of Pharmaceuticals

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Additive Manufacturing in Pharmaceuticals

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Abstract

A shift in treatment strategy from generalized to personal healthcare has sparked the interest for flexible production techniques capable of producing patient-specific dosage forms. Fused deposition modeling could be utilized for such personalized treatment, and its interest has grown rapidly, with over 350 published papers in the field of pharmaceutical science in the last decade. The advantages of the technique are indeed manifold. Apart from being desktop-sized, FDM has also been praised for its simplicity and cost-effectiveness. The aim of this chapter is to summarize 10 years of research on pharmaceutical FDM 3D-printing in a concise and comprehensive way. Therefore, this chapter first provides information about the FDM 3D-printing equipment and its process mechanism. Next, the typical formulation constituents and specific characterization techniques for the printed dosage forms will be discussed. Finally, a variety of possible pharmaceutical applications like oral therapies, transdermal or transmucosal films and implants will also be reviewed.

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  1. Laboratory of Pharmaceutical Technology, Ghent University, Ghent, Belgium

    Silke Henry, Valérie Vanhoorne & Chris Vervaet

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  1. Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Guwahati, Assam, India

    Subham Banerjee

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Henry, S., Vanhoorne, V., Vervaet, C. (2023). Fused Deposition Modeling (FDM) of Pharmaceuticals. In: Banerjee, S. (eds) Additive Manufacturing in Pharmaceuticals. Springer, Singapore. https://doi.org/10.1007/978-981-99-2404-2_2

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