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Surface Modification of Regenerative Cellulose (RC) for Biomedical Applications

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Regenerated Cellulose and Composites

Part of the book series: Engineering Materials ((ENG.MAT.))

Abstract

In modern green and sustainable chemistry, regenerative cellulose (RC) plays an increasingly critical role in science and engineering, including electronics and biomedical applications such as tissue engineering, drug delivery, and biosensing with its high biocompatibility and biodegradability, less toxicity, and high mechanical strength. RC can be surface modified through hydroxyl groups using ligands, polymers, metal nanoparticles, and carbon-based nanomaterials to highly chemical active and sophisticated materials for various biomedical applications. The surface-modified RC confers excellent chemical, electrical, optical, and mechanical properties that can selectively bind to the target biomolecules and cellular environments easily. This chapter reviews RC surface modification methods by using organic and inorganic nanomaterials for biomedical applications. Furthermore, this review summarizes the recent advances in adopting polymers and inorganic materials capable of functionalizing the RC surfaces and the effects of the guest molecule—RC composites in tissue engineering, biosensing, and wound dressing applications. This review aims to provide a comprehensive overview of the consistent improvement of functionalized RC and RC composites for highly sophisticated biomedical applications.

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Authors and Affiliations

  1. School of Chemical Engineering, College of Engineering, Universiti Teknologi MARA, 40450, Shah Alam, Selangor, Malaysia

    Mohamed Hasaan Hussain, Umairah Mohd Zaki, Noor Fitrah Abu Bakar, Huey Ling Tan, Norazah Abd Rahman & Amizon Azizan

  2. School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310, Skudai, Johor, Malaysia

    Nadia Adrus

  3. Department of Pharmacology, Faculty Medicine, Universiti Teknologi MARA Cawangan Selangor, Sungai Buloh Campus, 47000, Selangor, Sungai Buloh, Malaysia

    Muhammad Huzaimi Haron

  4. Integrative Pharmacogenomics Institute, Universiti Teknologi MARA Cawangan Selangor, Puncak Alam Campus, 42300 Puncak Alam, Selangor, Malaysia

    Lay Kek Teh

  5. Faculty of Pharmacy, Universiti Teknologi MARA Cawangan Selangor, Puncak Alam Campus, 42300 Puncak Alam, Selangor, Malaysia

    Lay Kek Teh

  6. School of Chemical Engineering, College of Engineering, Cawangan Pulau Pinang, Universiti Teknologi MARA, 13500 Permatang Pauh, Penang, Malaysia

    Mohamed Syazwan Osman

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  1. Mohamed Hasaan Hussain
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  2. Umairah Mohd Zaki
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Correspondence to Noor Fitrah Abu Bakar .

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  1. Department of Applied Science and Humanities (Chemistry), GL Bajaj Institute of Technology and Management, Greater Noida, India

    Mohd Shabbir

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Hussain, M.H. et al. (2023). Surface Modification of Regenerative Cellulose (RC) for Biomedical Applications. In: Shabbir, M. (eds) Regenerated Cellulose and Composites. Engineering Materials. Springer, Singapore. https://doi.org/10.1007/978-981-99-1655-9_4

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