Abstract
Functional foods offer vital nutrients that can protect against different diseases in humans. These functional foods are exclusively full of antioxidants that can remove many detrimental compounds including free radicals (ROS/RNS) to protect from adult stem cell damage to different diseases including cancer, diabetes, chronic obstructive pulmonary disease (COPD), and cardiovascular lesions, namely, fibrous obliterative pericarditis and rheumatoid granulomas, vasculitis, valvulitis, and nonspecific myocarditis. Functional foods are ingredients that give health benefits beyond the nutritional value. Some types of functional foods contain supplements or additional ingredients intended to recover health. Recently, scientific studies showed that functional foods rich in fruits and vegetables are important having anticancer effects of phytochemicals which are also focused to aim cancer stem cells (CSCs). Several preclinical and clinical investigations are still ongoing on the effects of dietary phytochemicals on adult stem cells and the prevention of aging and against CSCs of different cancers. The population of adult stem cells (ASCs) is reduced, unable to regenerate and reprogram, and showed the failure of tissue homeostasis during aging. The developing therapeutic methods with functional foods could modulate the major signaling pathways of losing adult stem cell populations, as well as could sustain healthy stem cell pool reprogramming to increase human lifespan.
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This work was part of the honors option project (HOP) of Andres Dominguez Solano mentored by Dr. Jayanta K. Das, at MDC Eduardo J. Padrón campus, Miami, FL, USA.
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Das, J.K., Mathuram, T.L., Solano, A.D., Das, M. (2023). Importance of Functional Foods Against Aging of Adult Stem Cells. In: Pathak, S., Banerjee, A., Duttaroy, A.K. (eds) Evidence-based Functional Foods for Prevention of Age-related Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-99-0534-8_11
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