Abstract
Intrauterine adhesions are bands of fibrous tissue that occur inside the endometrial cavity frequently in response to endometrial injury. The severity of this condition can range from thin strings of filmy tissue to complete obliteration of the cavity with subsequent amenorrhea and infertility among other clinical devastating consequences. Clinical challenges include primary prevention of adhesions and prevention of recurrent adhesions after surgical treatment. In this chapter, we provide an overview of the etiopathogenesis of intrauterine adhesions.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Dreisler E, Kjer JJ. Asherman’s syndrome: current perspectives on diagnosis and management. Int J Women’s Health. 2019;11:191–8.
Malhotra N, Bahadur A, Kalaivani M, Mittal S. Changes in endometrial receptivity in women with Asherman’s syndrome undergoing hysteroscopic adhesiolysis. Arch Gynecol Obstet. 2012;286(2):525–30.
Schenker JG. Etiology of and therapeutic approach to synechia uteri. Eur J Obstet Gynecol Reprod Biol. 1996;65(1):109–13.
Yu D, Wong YM, Cheong Y, Xia E, Li TC. Asherman syndrome—one century later. Fertil Steril. 2008;89(4):759–79.
Salazar CA, Isaacson K, Morris S. A comprehensive review of Asherman’s syndrome: causes, symptoms and treatment options. Curr Opin Obstet Gynecol. 2017;29(4):249–56.
Conforti A, Alviggi C, Mollo A, De Placido G, Magos A. The management of Asherman syndrome: a review of literature. Reprod Biol Endocrinol. 2013;11:118.
Wang X, Ma N, Sun Q, Huang C, Liu Y, Luo X. Elevated NF-kappaB signaling in Asherman syndrome patients and animal models. Oncotarget. 2017;8(9):15399–406.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Carugno, J., Timmons, D., Naguib, M.S. (2021). Etiopathogenesis of Asherman’s Syndrome. In: Manchanda, R. (eds) Intra Uterine Adhesions. Springer, Singapore. https://doi.org/10.1007/978-981-33-4145-6_2
Download citation
DOI: https://doi.org/10.1007/978-981-33-4145-6_2
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-33-4144-9
Online ISBN: 978-981-33-4145-6
eBook Packages: MedicineMedicine (R0)