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Point-of-Care Biosensors for Healthcare Applications

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Nanobiosensors for point-of-care medical diagnostics

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Abstract

In the healthcare sector, biosensors have been extensively used to detect pathogens, antigens, and biomarkers for different diseases/ailments from various biological samples like blood serum, plasma, urine, saliva, faecal matter, etc. Point-of-care (POC) biosensors are scaled down to compact devices that can detect diseases next to the patient to reduce the therapeutic turnaround time. Determination of blood sugar level for diabetes monitoring is the most widely used and commercially available, self-usable POC biosensor. Although biosensors exist for various diseases, there is still a challenge of making them POC because of characteristic requirements of the bioreceptors, such as the storage conditions, and fabrication techniques. Cardiovascular diseases, neural disease (stress), kidney disease, urinary tract infection, and other viral infections are some diseases that can be detected using a biosensor. POC biosensors are available for detecting some of these diseases. This book chapter discusses different POC biosensors for all the prominent diseases and conditions. A good number of rapid POC devices for mass testing and detection of coronavirus disease 2019 (COVID-19) were quickly developed, which helped in controlling the pandemic. Handheld electronic device systems to display the outputs and results of the biosensors are also available for many of the biosensors. The advancement of the Internet of things (IoT) made these biosensor devices linkable with a smartphone to make delivery of results possible for the doctors to analyse.

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Authors and Affiliations

  1. Department of Biomedical Engineering, North-Eastern Hill University, Shillong, Meghalaya, India

    Bethuel Daurai & Manashjit Gogoi

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  1. Bethuel Daurai
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  2. Manashjit Gogoi
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  1. Department of Biomedical Engineering, North-Eastern Hill University, Shillong, Meghalaya, India

    Manashjit Gogoi

  2. Department of Biosciences and Bioengineering, Indian Institute of Technology, Guwahati, Assam, India

    Sanjukta Patra

  3. Department of Biosciences and Bioengineering, Indian Institute of Technology, Guwahati, Assam, India

    Debasree Kundu

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Daurai, B., Gogoi, M. (2022). Point-of-Care Biosensors for Healthcare Applications. In: Gogoi, M., Patra, S., Kundu, D. (eds) Nanobiosensors for point-of-care medical diagnostics . Springer, Singapore. https://doi.org/10.1007/978-981-19-5141-1_1

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