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Progress in Cardiorespiratory Ischemia-Reperfusion Injury

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Sudden Death

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Abstract

Sudden cardiac arrest (SCA) is a common cause of death in emergency departments, although SCA treatment has been improved with the improvement of medical and health care, the improvement of cardiopulmonary resuscitation technology, and the use of drugs and other therapeutic measures. However, the survival and discharge rate is still not optimistic. Post-cardiac arrest syndrome (PCAS) is a complex combination of pathophysiological processes, consisting of post-cardiac arrest brain injury, post-cardiac arrest myocardial dysfunction, systemic ischemia-reperfusion response, and persistent precipitating pathology. This part will focus on the latest progress of post-resuscitation myocardial dysfunction, mainly focusing on the mechanism of ischemia-reperfusion injury, to provide basis for clinical treatment.

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Authors and Affiliations

  1. Department of Emergency Medicine and Chest Pain Center, Qilu Hospital of Shandong University, Jinan, China

    Chang Pan, Qiuhuan Yuan & Feng Xu

  2. Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Institute of Emergency and Critical Care Medicine of Shandong University, Qilu Hospital of Shandong University, Jinan, China

    Chang Pan, Qiuhuan Yuan & Feng Xu

  3. Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Shandong Province, Shandong Provincial Engineering Laboratory for Emergency and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China

    Chang Pan, Qiuhuan Yuan & Feng Xu

  4. The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese Ministry of Health and Chinese Academy of Medical Sciences; The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan, China

    Chang Pan, Qiuhuan Yuan & Feng Xu

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  1. Chang Pan
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  1. Emergency Department, The First Medical Center of Chinese PLA General Hospital, Beijing, China

    Haiyan Zhu

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Pan, C., Yuan, Q., Xu, F. (2021). Progress in Cardiorespiratory Ischemia-Reperfusion Injury. In: Zhu, H. (eds) Sudden Death. Springer, Singapore. https://doi.org/10.1007/978-981-15-7002-5_6

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