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Biodiversity of Marine Actinobacteria in Indonesia and Their Potential to Produce Bioactive Compounds

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Marine Niche: Applications in Pharmaceutical Sciences

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Abstract

Increased microbial resistance due to the use of antibiotics and the emergence of new pathogenic microbes has inspired the search for new antibiotics from microbes. Some literature states that marine actinobacteria have a lot of potential to produce bioactive compounds, thus increasing the interest of researchers.

It was reported that there are more than 25,000 known microbial bioactive compounds, 75% of which are produced by actinobacteria (most of which are the genus Streptomyces), and a further 25% by the fungus, Bacillus spp. and other bacteria. More than 10,000 antibiotics are known to have been produced from the genus Streptomyces. This makes the genus Streptomyces very important than others. The discovery of rare and new actinobacteria is very important and interesting for the discovery of bioactive compounds because of the increasing need for the development of new and potential antimicrobial agents. Provision of access to new sources of bioactive compounds in the form of modern technology is needed for the detection and isolation of marine actinobacteria and their bioactive compounds. This process is then continued through the development of improved cultivation methods with molecular technologies that needs to be done intensively so as to produce antibiotic compounds with novel actinobacteria including new species as previously reported.

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Authors and Affiliations

  1. Research and Development Center for Marine and Fisheries Product Processing and Biotechnology, Jakarta, Indonesia

    Ifah Munifah & Hari Eko Irianto

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  1. Ifah Munifah
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  2. Hari Eko Irianto
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Editors and Affiliations

  1. Department of Science & Technology, Gujarat Biotechnology Research Centre (GBRC), Gandhinagar, Gujarat, India

    Neelam M Nathani

  2. Department of Science & Technology, Gujarat Biotechnology Research Centre (GBRC), Gandhinagar, Gujarat, India

    Chandrashekar Mootapally

  3. Department of Life Sciences, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India

    Indra R. Gadhvi

  4. Department of Botany, Gujarat University, Ahmedabad, Gujarat, India

    Bharat Maitreya

  5. Department of Science & Technology, Gujarat Biotechnology Research Centre (GBRC), Gandhinagar, Gujarat, India

    Chaitanya G. Joshi

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Munifah, I., Irianto, H.E. (2020). Biodiversity of Marine Actinobacteria in Indonesia and Their Potential to Produce Bioactive Compounds. In: Nathani, N.M., Mootapally, C., Gadhvi, I.R., Maitreya, B., Joshi, C.G. (eds) Marine Niche: Applications in Pharmaceutical Sciences . Springer, Singapore. https://doi.org/10.1007/978-981-15-5017-1_7

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