Abstract
Current demographic trends, the rise of chronic diseases, the accessibility of inexpensive generic treatments, and the emergence of “lifestyle” drugs have been the key to increased pharmaceutical medicine use throughout the world. These pharmaceuticals are now the group of emerging contaminants with rising concern in the scientific world due to their presence in surface water, such as lake and river, groundwater, soil, and even drinking water and their associated impact on invertebrates, vertebrates, and ecosystem structure and function. The two main routes of such contaminations are (1) when such drugs taken are excreted in faces and urine and (2) when unused drugs are thrown down. Research undertaken has found that 60–80% of these pharmaceutical medicines are flushed down the toilet or dumped as regular household waste that ends up in sewage treatment plants, which are generally not designed to remove such pollutants from wastewater. Bioremediation is a process where degradation of contamination is done with the help of different microorganisms, which is one of the cost-effective methods that has been used until now. Though there are some interesting reports on the bioremediation of pharmaceuticals from water, further research is crucial for the systematic development of novel technologies to deal with such emerging contaminants. This chapter, therefore, is focused on summarizing and consolidating findings from the current state of the art in the area of pharmaceutical bioremediation.
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References
Ahmed MB, Zhou JL, Hao Ngo H, Guo W, Thomaidis NS, Xu J (2017) Progress in the biological and chemical treatment technologies for emerging contaminant removal from wastewater: a critical review. J Hazard Mater 323:274–298. https://doi.org/10.1016/j.jhazmat.2016.04.045
Al Qarni H, Collier P, O’Keeffe J, Akunna J (2016) Investigating the removal of some pharmaceutical compounds in hospital wastewater treatment plants operating in Saudi Arabia. Environ Sci Pollut Res Int 23:13003–13014. https://doi.org/10.1007/s11356-016-6389-7
Alharbi SK, Nghiem LD, van de Merwe JP, Leusch FDL, Asif MB, Hai FI, Price WE (2019) Degradation of diclofenac, trimethoprim, carbamazepine, and sulfamethoxazole by laccase from Trametes versicolor: transformation products and toxicity of treated effluent. Biocatal Biotransformation:1–10. https://doi.org/10.1080/10242422.2019.1580268
Awfa D, Ateia M, Fujii M, Yoshimura C (2019) Novel magnetic carbon nanotube-TiO2 composites for solar light photocatalytic degradation of pharmaceuticals in the presence of natural organic matter. J Water Process Eng 31:100836. https://doi.org/10.1016/J.JWPE.2019.100836
Beausse J (2004) Selected drugs in solid matrices: a review of environmental determination, occurrence and properties of principal substances. TrAC Trends Anal Chem 23:753–761. https://doi.org/10.1016/j.trac.2004.08.005
Bernabeu A, Vercher RF, Santos-Juanes L, Simón PJ, Lardín C, Martínez MA, Vicente JA, González R, Llosá C, Arques A, Amat AM (2011) Solar photocatalysis as a tertiary treatment to remove emerging pollutants from wastewater treatment plant effluents. Catal Today 161:235–240. https://doi.org/10.1016/J.CATTOD.2010.09.025
Bessa VS, Moreira I, Murgolo S, Mascolo G, Castro PML (2017a) Biodegradation of carbamazepine and diclofenac by bacterial strain Labrys portucalensis. In: ICEBB 2017 19th international conference on environmental biotechnology and bioremediation
Bessa VS, Moreira IS, Tiritan ME, Castro PML (2017b) Enrichment of bacterial strains for the biodegradation of diclofenac and carbamazepine from activated sludge. Int Biodeterior Biodegradation 120:135–142. https://doi.org/10.1016/J.IBIOD.2017.02.008
Bock EM, Coleman B, Easton ZM (2016) Effect of biochar on nitrate removal in a pilot-scale denitrifying bioreactor. J Environ Qual 45:762. https://doi.org/10.2134/jeq2015.04.0179
Boucenna A, Oturan N, Chabani M, Bouafia-Chergui S, Oturan MA (2019) Degradation of Nystatin in aqueous medium by coupling UV-C irradiation, H2O2 photolysis, and photo-Fenton processes. Environ Sci Pollut Res 26:1–13. https://doi.org/10.1007/s11356-019-05530-2
Brillas E, Sirés I, Oturan MA (2009) Electro-Fenton process and related electrochemical technologies based on Fenton’s reaction chemistry. Chem Rev 109:6570–6631. https://doi.org/10.1021/cr900136g
Brune K, Patrignani P (2015) New insights into the use of currently available non-steroidal anti-inflammatory drugs. J Pain Res 8:105–118. https://doi.org/10.2147/JPR.S75160
Buchicchio A, Bianco G, Sofo A, Masi S, Caniani D (2016) Biodegradation of carbamazepine and clarithromycin by Trichoderma harzianum and Pleurotus ostreatus investigated by liquid chromatography—high-resolution tandem mass spectrometry (FTICR MS-IRMPD). Sci Total Environ 557–558:733–739. https://doi.org/10.1016/J.SCITOTENV.2016.03.119
Chakraborty P, Show S, Banerjee S, Halder G (2018) Mechanistic insight into sorptive elimination of ibuprofen employing bi-directional activated biochar from sugarcane bagasse: performance evaluation and cost estimation. J Environ Chem Eng 6:5287–5300. https://doi.org/10.1016/j.jece.2018.08.017
Chakraborty P, Show S, Ur Rahman W, Halder G (2019) Linearity and non-linearity analysis of isotherms and kinetics for ibuprofen remotion using superheated steam and acid modified biochar. Process Saf Environ Prot 126:193–204. https://doi.org/10.1016/j.psep.2019.04.011
Chen B, Zhou D, Zhu L (2008) Transitional adsorption and partition of nonpolar and polar aromatic contaminants by biochars of pine needles with different pyrolytic temperatures. Environ Sci Technol 42:5137–5143. https://doi.org/10.1021/es8002684
Chen T, Luo L, Deng S, Shi G, Zhang S, Zhang Y, Deng O, Wang L, Zhang J, Wei L (2018) Sorption of tetracycline on H3PO4 modified biochar derived from rice straw and swine manure. Bioresour Technol 267:431–437. https://doi.org/10.1016/J.BIORTECH.2018.07.074
Cheng J, Ye Q, Li K, Liu J, Zhou J (2018) Removing ethinylestradiol from wastewater by microalgae mutant Chlorella PY-ZU1 with CO2 fixation. Bioresour Technol 249:284–289. https://doi.org/10.1016/j.biortech.2017.10.036
Daughton CG, Ternes TA (1999) Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ Health Perspect 107:907–938. https://doi.org/10.1289/ehp.99107s6907
Dębska J, Kot-Wasik A, Namieśnik J (2004) Fate and analysis of pharmaceutical residues in the aquatic environment. Crit Rev Anal Chem 34:51–67. https://doi.org/10.1080/10408340490273753
Doll TE, Frimmel FH (2003) Fate of pharmaceuticals––photodegradation by simulated solar UV-light. Chemosphere 52:1757–1769. https://doi.org/10.1016/S0045-6535(03)00446-6
Du Y, Zhang S, Guo R, Chen J (2015) Understanding the algal contribution in combined UV-algae treatment to remove antibiotic cefradine. RSC Adv 5:59953–59959. https://doi.org/10.1039/C5RA10806C
Esterhuizen-Londt M, Schwartz K, Pflugmacher S (2016) Using aquatic fungi for pharmaceutical bioremediation: uptake of acetaminophen by Mucor hiemalis does not result in an enzymatic oxidative stress response. Fungal Biol 120:1249–1257. https://doi.org/10.1016/j.funbio.2016.07.009
Fan S, Wang Y, Li Y, Wang Z, Xie Z, Tang J (2018) Removal of tetracycline from aqueous solution by biochar derived from rice straw. Environ Sci Pollut Res 25:29529–29540. https://doi.org/10.1007/s11356-018-2976-0
Fortunato MS, Fuentes Abril NP, Martinefski M, Trípodi V, Papalia M, Rádice M, Gutkind G, Gallego A, Korol SE (2016) Aerobic degradation of ibuprofen in batch and continuous reactors by an indigenous bacterial community. Environ Technol 37:2617–2626. https://doi.org/10.1080/09593330.2016.1156773
Garcia-Rodríguez A, Matamoros V, Fontàs C, Salvadó V (2015) The influence of Lemna sp. and Spirogyra sp. on the removal of pharmaceuticals and endocrine disruptors in treated wastewaters. Int J Environ Sci Technol 12:2327–2338. https://doi.org/10.1007/s13762-014-0632-x
Garza-Campos B, Morales-Acosta D, Hernández-Ramírez A, Guzmán-Mar JL, Hinojosa-Reyes L, Manríquez J, Ruiz-Ruiz EJ (2018) Air diffusion electrodes based on synthetized mesoporous carbon for application in amoxicillin degradation by electro-Fenton and solar photo electro-Fenton. Electrochim Acta 269:232–240. https://doi.org/10.1016/j.electacta.2018.02.139
Gojkovic Z, Lindberg RH, Tysklind M, Funk C (2019) Northern green algae have the capacity to remove active pharmaceutical ingredients. Ecotoxicol Environ Saf 170:644–656. https://doi.org/10.1016/j.ecoenv.2018.12.032
Hachi M, Chergui A, Yeddou AR, Selatnia A, Cabana H (2017) Removal of acetaminophen and carbamazepine in single and binary systems with immobilized laccase from Trametes hirsuta. Biocatal Biotransformation 35:51–62. https://doi.org/10.1080/10242422.2017.1280032
He Y, Sutton NB, Rijnaarts HHH, Langenhoff AAM (2016) Degradation of pharmaceuticals in wastewater using immobilized TiO2 photocatalysis under simulated solar irradiation. Appl Catal B Environ 182:132–141. https://doi.org/10.1016/J.APCATB.2015.09.015
Heberer T (2002) Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicol Lett 131:5–17. https://doi.org/10.1016/S0378-4274(02)00041-3
Inyang M, Gao B, Zimmerman A, Zhou Y, Cao X (2015) Sorption and cosorption of lead and sulfapyridine on carbon nanotube-modified biochars. Environ Sci Pollut Res 22:1868–1876. https://doi.org/10.1007/s11356-014-2740-z
Jelic A, Gros M, Ginebreda A, Cespedes-Sánchez R, Ventura F, Petrovic M, Barcelo D (2011) Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment. Water Res 45:1165–1176. https://doi.org/10.1016/J.WATRES.2010.11.010
Kanakaraju D, Motti CA, Glass BD, Oelgemöller M (2016) Solar photolysis versus TiO2-mediated solar photocatalysis: a kinetic study of the degradation of naproxen and diclofenac in various water matrices. Environ Sci Pollut Res 23:17437–17448. https://doi.org/10.1007/s11356-016-6906-8
Legrini O, Oliveros E, Braun AM (1993) Photochemical processes for water treatment. Chem Rev 93:671–698. https://doi.org/10.1021/cr00018a003
Li T, Han X, Liang C, Shohag MJI, Yang X (2015) Environmental technology sorption of sulphamethoxazole by the biochars derived from rice straw and alligator flag sorption of sulphamethoxazole by the biochars derived from rice straw and alligator flag. Environ Technol 36:245–253. https://doi.org/10.1080/09593330.2014.943299
Li G, Zhu W, Zhu L, Chai X (2016) Effect of pyrolytic temperature on the adsorptive removal of p-benzoquinone, tetracycline, and polyvinyl alcohol by the biochars from sugarcane bagasse. Korean J Chem Eng 33:2215–2221. https://doi.org/10.1007/s11814-016-0067-9
López-Serna R, Kasprzyk-Hordern B, Petrović M, Barceló D (2013) Multi-residue enantiomeric analysis of pharmaceuticals and their active metabolites in the Guadalquivir River basin (South Spain) by chiral liquid chromatography coupled with tandem mass spectrometry. Anal Bioanal Chem 405:5859–5873. https://doi.org/10.1007/s00216-013-6900-7
Magioglou E, Frontistis Z, Vakros J, Manariotis ID, Mantzavinos D, Magioglou E, Frontistis Z, Vakros J, Manariotis ID, Mantzavinos D (2019) Activation of Persulfate by biochars from valorized olive stones for the degradation of Sulfamethoxazole. Catalysts 9:419. https://doi.org/10.3390/catal9050419
Magureanu M, Mandache NB, Parvulescu VI (2015) Degradation of pharmaceutical compounds in water by non-thermal plasma treatment. Water Res 81:124–136. https://doi.org/10.1016/j.watres.2015.05.037
Marchlewicz A, Domaradzka D, Guzik U, Wojcieszyńska D (2016) Bacillus thuringiensis B1(2015b) is a gram-positive Bacteria able to degrade naproxen and ibuprofen. Water Air Soil Pollut 227:197. https://doi.org/10.1007/s11270-016-2893-0
Maurer D, Koziel J, Kalus K, Andersen D, Opalinski S, Maurer DL, Koziel JA, Kalus K, Andersen DS, Opalinski S (2017) Pilot-scale testing of non-activated biochar for swine manure treatment and mitigation of Ammonia, hydrogen sulfide, odorous volatile organic compounds (VOCs), and greenhouse gas emissions. Sustainability 9:929. https://doi.org/10.3390/su9060929
Mondal S, Bobde K, Aikat K, Halder G (2016) Biosorptive uptake of ibuprofen by steam activated biochar derived from mung bean husk: equilibrium, kinetics, thermodynamics, modeling and eco-toxicological studies. J Environ Manag 182:581–594. https://doi.org/10.1016/J.JENVMAN.2016.08.018
Monteoliva-García A, Martín-Pascual J, Muñío MM, Poyatos JM (2019) Removal of carbamazepine, ciprofloxacin and ibuprofen in real urban wastewater by using light-driven advanced oxidation processes. Int J Environ Sci Technol 16:6005. https://doi.org/10.1007/s13762-019-02365-9
Morasch B, Bonvin F, Reiser H, Grandjean D, de Alencastro LF, Perazzolo C, Chèvre N, Kohn T (2010) Occurrence and fate of micropollutants in the Vidy Bay of Lake Geneva, Switzerland. Part II: Micropollutant removal between wastewater and raw drinking water. Environ Toxicol Chem 29. https://doi.org/10.1002/etc.222
Moreira FC, Soler J, Alpendurada MF, Boaventura RAR, Brillas E, Vilar VJP (2016) Tertiary treatment of a municipal wastewater toward pharmaceuticals removal by chemical and electrochemical advanced oxidation processes. Water Res 105:251–263. https://doi.org/10.1016/J.WATRES.2016.08.036
Murillo-Sierra JC, Ruiz-Ruiz E, Hinojosa-Reyes L, Guzmán-Mar JL, Machuca-Martínez F, Hernández-Ramírez A (2018) Sulfamethoxazole mineralization by solar photo electro-Fenton process in a pilot plant. Catal Today 313:175–181. https://doi.org/10.1016/j.cattod.2017.11.003
Muter O, P Erkons I, Selga T, Berzins A, Gudra D, Radovica-Spalvina I, Fridmanis D, Bartkevics V (2017) Removal of pharmaceuticals from municipal wastewaters at laboratory scale by treatment with activated sludge and biostimulation. Sci Total Environ 584–585:402–413. https://doi.org/10.1016/J.SCITOTENV.2017.01.023
Nguyen T-T, Bui X-T, Luu V-P, Nguyen P-D, Guo W, Ngo H-H (2017) Removal of antibiotics in sponge membrane bioreactors treating hospital wastewater: comparison between hollow fiber and flat sheet membrane systems. Bioresour Technol 240:42–49. https://doi.org/10.1016/J.BIORTECH.2017.02.118
OECD Indicators (2017) Health at a Glance 2017, OECD Publishing, Paris. https://doi.org/10.1787/health_glance-2017-en
Perazzolo C, Morasch B, Kohn T, Magnet A, Thonney D, Chèvre N (2010) Occurrence and fate of micropollutants in the Vidy Bay of Lake Geneva, Switzerland. Part I: Priority list for environmental risk assessment of pharmaceuticals. Environ Toxicol Chem 29. https://doi.org/10.1002/etc.221
Pereira VJ, Linden KG, Weinberg HS (2007) Evaluation of UV irradiation for photolytic and oxidative degradation of pharmaceutical compounds in water. Water Res 41:4413–4423. https://doi.org/10.1016/J.WATRES.2007.05.056
Perini JA d L, Silva BC e, Tonetti AL, Nogueira RFP (2017) Photo-Fenton degradation of the pharmaceuticals ciprofloxacin and fluoxetine after anaerobic pre-treatment of hospital effluent. Environ Sci Pollut Res 24:6233–6240. https://doi.org/10.1007/s11356-016-7416-4
Perini JAL, Tonetti AL, Vidal C, Montagner CC, Nogueira RFP (2018) Simultaneous degradation of ciprofloxacin, amoxicillin, sulfathiazole and sulfamethazine, and disinfection of hospital effluent after biological treatment via photo-Fenton process under ultraviolet germicidal irradiation. Appl Catal B Environ 224:761–771. https://doi.org/10.1016/j.apcatb.2017.11.021
Petrie B, Barden R, Kasprzyk-Hordern B (2015) A review on emerging contaminants in wastewaters and the environment: current knowledge, understudied areas and recommendations for future monitoring. Water Res 72:3–27. https://doi.org/10.1016/j.watres.2014.08.053
Petrović M, Gonzalez S, Barceló D (2003) Analysis and removal of emerging contaminants in wastewater and drinking water. TrAC Trends Anal Chem 22:685–696. https://doi.org/10.1016/S0165-9936(03)01105-1
Popa C, Favier L, Dinica R, Semrany S, Djelal H, Amrane A, Bahrim G (2014) Potential of newly isolated wild Streptomyces strains as agents for the biodegradation of a recalcitrant pharmaceutical, carbamazepine. Environ Technol 35:3082–3091. https://doi.org/10.1080/09593330.2014.931468
Prasertkulsak S, Chiemchaisri C, Chiemchaisri W, Yamamoto K (2019) Removals of pharmaceutical compounds at different sludge particle size fractions in membrane bioreactors operated under different solid retention times. J Hazard Mater 368:124–132. https://doi.org/10.1016/J.JHAZMAT.2019.01.050
Rajaram T, Das A (2008) Water pollution by industrial effluents in India: discharge scenarios and case for participatory ecosystem specific local regulation. Futures 40:56–69. https://doi.org/10.1016/J.FUTURES.2007.06.002
Richardson ML, Bowron JM (1985) The fate of pharmaceutical chemicals in the aquatic environment. J Pharm Pharmacol 37(1):1–12. https://doi.org/10.1111/j.2042-7158.1985.tb04922.x
Rodarte-Morales AI, Feijoo G, Moreira MT, Lema JM (2012) Biotransformation of three pharmaceutical active compounds by the fungus Phanerochaete chrysosporium in a fed batch stirred reactor under air and oxygen supply. Biodegradation 23:145–156. https://doi.org/10.1007/s10532-011-9494-9
Salem NA, Yakoot SM (2016) Non-steroidal anti-inflammatory drug, ibuprofen adsorption using Rice straw based biochar. Int J Pharmacol 12:729–736. https://doi.org/10.3923/ijp.2016.729.736
Santoke H, Song W, Cooper WJ, Greaves J, Miller GE (2009) Free-radical-induced oxidative and reductive degradation of fluoroquinolone pharmaceuticals: kinetic studies and degradation mechanism. J Phys Chem A 113:7846–7851. https://doi.org/10.1021/jp9029453
Sardar K, Rashid MA, Khandoker MR, Khan A (2016) Anticonvulsants and antidepressants in chronic pain management. J Recent Adv Pain 2:90–93. https://doi.org/10.5005/jp-journals-10046-0050
Sarganas G, Knopf H, Grams D, Neuhauser HK (2016) Trends in antihypertensive medication use and blood pressure control among adults with hypertension in Germany. Am J Hypertens 29:104–113. https://doi.org/10.1093/ajh/hpv067
Saritha P, Aparna C, Himabindu V, Anjaneyulu Y (2007) Comparison of various advanced oxidation processes for the degradation of 4-chloro-2 nitrophenol. J Hazard Mater 149:609–614. https://doi.org/10.1016/J.JHAZMAT.2007.06.111
Sauvêtre A, Schröder P (2015) Uptake of carbamazepine by rhizomes and endophytic bacteria of Phragmites australis. Front Plant Sci 6:83. https://doi.org/10.3389/fpls.2015.00083
Shemer H, Kunukcu YK, Linden KG (2006) Degradation of the pharmaceutical metronidazole via UV, Fenton and photo-Fenton processes. Chemosphere 63:269–276. https://doi.org/10.1016/J.CHEMOSPHERE.2005.07.029
Song W, Cooper WJ, Mezyk SP, Greaves J, Peake BM (2008) Free radical destruction of β-blockers in aqueous solution. Environ Sci Technol 42:1256–1261. https://doi.org/10.1021/es702245n
Sun J, Luo Q, Wang D, Wang Z (2015) Occurrences of pharmaceuticals in drinking water sources of major river watersheds, China. Ecotoxicol Environ Saf 117:132–140. https://doi.org/10.1016/j.ecoenv.2015.03.032
Tomić M, Micov A, Pecikoza U, Stepanović-Petrović R (2017) Clinical uses of nonsteroidal anti-inflammatory drugs (NSAIDs) and potential benefits of NSAIDs modified-release preparations. In: Microsized nanosized carriers nonsteroidal anti-inflammatory drugs, pp 1–29. https://doi.org/10.1016/B978-0-12-804017-1.00001-7
Vasiliadou IA, Molina R, Pariente MI, Christoforidis KC, Martinez F, Melero JA (2019) Understanding the role of mediators in the efficiency of advanced oxidation processes using white-rot fungi. Chem Eng J 359:1427–1435. https://doi.org/10.1016/J.CEJ.2018.11.035
Ventola CL (2015) The antibiotic resistance crisis: Part 1: causes and threats. P T 40:277–283
Vithanage M, Mayakaduwa SS, Herath I, Ok YS, Mohan D (2016) Kinetics, thermodynamics and mechanistic studies of carbofuran removal using biochars from tea waste and rice husks. Chemosphere 150:781–789. https://doi.org/10.1016/J.CHEMOSPHERE.2015.11.002
Wang Y, Lu J, Wu J, Liu Q, Zhang H, Jin S, Wang Y, Lu J, Wu J, Liu Q, Zhang H, Jin S (2015) Adsorptive removal of Fluoroquinolone antibiotics using bamboo biochar. Sustainability 7:12947–12957. https://doi.org/10.3390/su70912947
Wang X, Zhang J, Chang VWC, She Q, Tang CY (2018) Removal of cytostatic drugs from wastewater by an anaerobic osmotic membrane bioreactor. Chem Eng J 339:153–161. https://doi.org/10.1016/J.CEJ.2018.01.125
Wenk J, von Gunten U, Canonica S (2011) Effect of dissolved organic matter on the transformation of contaminants induced by excited triplet states and the hydroxyl radical. Environ Sci Technol 45:1334–1340. https://doi.org/10.1021/es102212t
WHO (2015) The top 10 causes of death [WWW document]. http://who.int/mediacentre/factsheets/fs310/en/
Wittebolle L, Boon N, Vanparys B, Heylen K, De Vos P, Verstraete W (2005) Failure of the ammonia oxidation process in two pharmaceutical wastewater treatment plants is linked to shifts in the bacterial communities. J Appl Microbiol 99:997–1006. https://doi.org/10.1111/j.1365-2672.2005.02731.x
Xu B, Xue G, Yang X (2018) Isolation and application of an ibuprofen-degrading bacterium to a biological aerated filter for the treatment of micro-polluted water. Front Environ Sci Eng 12:15. https://doi.org/10.1007/s11783-018-1080-5
Yao Y, Zhang Y, Gao B, Chen R, Wu F (2018) Removal of sulfamethoxazole (SMX) and sulfapyridine (SPY) from aqueous solutions by biochars derived from anaerobically digested bagasse. Environ Sci Pollut Res 25:25659–25667. https://doi.org/10.1007/s11356-017-8849-0
Yi S, Gao B, Sun Y, Wu J, Shi X, Wu B, Hu X (2016) Removal of levofloxacin from aqueous solution using rice-husk and wood-chip biochars. Chemosphere 150:694–701. https://doi.org/10.1016/J.CHEMOSPHERE.2015.12.112
Zeng Z, Tan X, Liu Y, Tian S, Zeng G, Jiang L, Liu S, Li J, Liu N, Yin Z (2018a) Comprehensive adsorption studies of doxycycline and ciprofloxacin antibiotics by biochars prepared at different temperatures. Front Chem 6:80. https://doi.org/10.3389/fchem.2018.00080
Zeng Z, Tian S, Liu Y, Tan X, Zeng G, Jiang L, Yin Z, Liu N, Liu S, Li J (2018b) Comparative study of rice husk biochars for aqueous antibiotics removal. J Chem Technol Biotechnol 93:1075–1084. https://doi.org/10.1002/jctb.5464
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Chhaya, Raychoudhury, T., Prajapati, S.K. (2020). Bioremediation of Pharmaceuticals in Water and Wastewater. In: Shah, M. (eds) Microbial Bioremediation & Biodegradation. Springer, Singapore. https://doi.org/10.1007/978-981-15-1812-6_16
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