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Chitosan for Tissue Engineering

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Novel Biomaterials for Regenerative Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1077))

Abstract

Chitosan, a deacetylated chitin, is one of the few natural polymers similar to glycosaminoglycans (GAGs) widely distributed throughout connective tissues. It has been believed that the excellent biocompatibility of chitosan is largely attributed to this structural similarity. Chitosan is also known to possess biodegradability, antimicrobial activity and low toxicity and immunogenicity which are essential for scaffolds. In addition, the existence of free amine groups in its backbone chain enables further chemical modifications to create the additional biomedical functionality. For these reasons, chitosan has found a tremendous variety of biomedical applications in recent years. This chapter introduces the basic contents of chitosan and discusses its applications to artificial skin, artificial bone, and artificial cartilage in tissue engineering purpose.

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Authors and Affiliations

  1. Laboratory of Tissue Engineering, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea

    Chun-Ho Kim & Sang Jun Park

  2. Institute of Cell and Tissue Engineering, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Dae Hyeok Yang

  3. Institute of Cell and Tissue Engineering, Department of Biomedical Sciences, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Heung Jae Chun

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  1. Chun-Ho Kim
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Correspondence to Heung Jae Chun .

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Editors and Affiliations

  1. The Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. Korea Institute of Science and Technology, Seoul, Korea (Republic of)

    Kwideok Park

  3. Korea Institute of Radiological and Medical Sciences, Seoul, Korea (Republic of)

    Chun-Ho Kim

  4. Chonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Kim, CH., Park, S.J., Yang, D.H., Chun, H.J. (2018). Chitosan for Tissue Engineering. In: Chun, H., Park, K., Kim, CH., Khang, G. (eds) Novel Biomaterials for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1077. Springer, Singapore. https://doi.org/10.1007/978-981-13-0947-2_25

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