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An overview of Helicobacter pylori epidemiology studies

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Helicobacter pylori

Abstract

It is well accepted that gastric carcinogenesis is a multistep and a multifactorial process with a sequential evolution from chronic gastritis, followed by atrophy, intestinal metaplasia, dysplasia and eventually carcinoma1. Several environmental factors including Helicobacter pylori, excessive intake of salt, bile reflux, N-nitroso compounds and a deficiency of antioxidants, have been linked with different stages of gastric carcinogenesisl. Among these risk factors, H. pylori is regarded as a trigger for the sequence of carcinogenesis since there is strong evidence for H. pylori infection as a cause of chronic atrophic gastritis and also intestinal metaplasia, which is a possible precancerous lesion2–4.

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Authors
  1. J.-Q. Huang
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  2. R. H. Hunt
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Editor information

Editors and Affiliations

  1. Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada

    Richard H. Hunt (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Department of Gastroenterology and Hepatology, Academic Medical Centre, 9 Meibergdreef, 1105 AZ, Amsterdam, The Netherlands

    Guido N. J. Tytgat (Professor) (Professor)

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© 1998 Springer Science+Business Media Dordrecht

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Huang, JQ., Hunt, R.H. (1998). An overview of Helicobacter pylori epidemiology studies. In: Hunt, R.H., Tytgat, G.N.J. (eds) Helicobacter pylori. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4882-5_32

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  • DOI: https://doi.org/10.1007/978-94-011-4882-5_32

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6046-2

  • Online ISBN: 978-94-011-4882-5

  • eBook Packages: Springer Book Archive

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