Intragenic suppression: Stalker, a retrovirus-like transposable element, can compensate for a deficiency at the cut locus of Drosophila melanogaster

  • V. A. Mogila
  • A. B. Ladvishenko
  • O. B. Simonova
  • T. I. Gerasimova
Part of the Contemporary Issues in Genetics and Evolution book series (CIGE, volume 1)


A number of mutations at the cut locus were induced by non-precise exision of a silent P-element insertion which resulted in deletions at the regulatory region of the locus. Unexpectedly, a reversion of one of these mutations was found, which appears as a result of insertion of Stalker (a retrovirus-like mobile element) near the 1.3 kb deletion. Thus an insertion of a retrovirus-like mobile element can suppress the deficiency at the regulatory region of a gene.


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Copyright information

© Springer Science+Business Media Dordrecht 1993

Authors and Affiliations

  • V. A. Mogila
    • 1
  • A. B. Ladvishenko
    • 1
  • O. B. Simonova
    • 1
  • T. I. Gerasimova
    • 1
  1. 1.Institute of Gene BiologyAcademy of Sciences of the USSRMoscowRussia

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