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Theoretical Studies of SN2 Reactions

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Quantum Theory of Chemical Reactions

Part of the book series: Quantum Theory of Chemical Reactions ((QTCR,volume 1))

Abstract

The nucleophilic substitution is an heterolytic reaction of the type

Y is called the nucleophile (usually an anion or a neutral base), X is called the leaving group. The atom which undergoes the substitution (usually a carbon atom in what follows) is called the electrophilic center. Two mechanisms are generally considered for the nucleophilic substitutions 1:

the SN1 unimolecular substitution, which takes place in two steps:

the first step corresponding to a slow and reversible dissociation to a cationic species. This mechanism usually leads to the racemization of an optically active substrate.

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Authors and Affiliations

  1. Université Louis Pasteur, E.R. n° 139 du CNRS, Strasbourg, France

    A. Dedieu & A. Veillard

Authors
  1. A. Dedieu
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  2. A. Veillard
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Editor information

Editors and Affiliations

  1. CNRS, Centre de Mécanique Ondulatoire Appliquée, Paris, France

    Raymond Daudel

  2. CNRS, Institut de Biologie Physico-Chimique, Paris, France

    Alberte Pullman

  3. CNRS, Laboratoire de Chimie Théorique, Université de Paris Sud, Orsay, France

    Lionel Salem

  4. CNRS, Université Louis Pasteur, Strasbourg, France

    Alain Veillard

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© 1979 D. Reidel Publishing Company

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Dedieu, A., Veillard, A. (1979). Theoretical Studies of SN2 Reactions. In: Daudel, R., Pullman, A., Salem, L., Veillard, A. (eds) Quantum Theory of Chemical Reactions. Quantum Theory of Chemical Reactions, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9516-1_4

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  • DOI: https://doi.org/10.1007/978-94-009-9516-1_4

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-9518-5

  • Online ISBN: 978-94-009-9516-1

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