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Metastatic Disease to the Lung in the Human

  • Chapter
Metastasis / Dissemination

Part of the book series: Cancer Growth and Progression ((CAGP,volume 8))

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Abstract

In the natural history of a tumor, the potential for metastases exists early. In the venous effluent of an isolated adenocarcinoma of a mouse ovary, an astonishing 3–4 × 106 cells per gram of tumor was released during 24 hours (9). Although it appears that metastatic spread is a random event, both experimental and clinical observations suggest that it is a consequence of complex interactions. Although the mechanisms are unclear, there is evidence for active organ selection by the metastatic tumor cells.

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Authors
  1. M. Wayne Flye
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Editors and Affiliations

  1. Pittsburgh Cancer Institute, Pittsburgh, Pa, USA

    Elizier L. Gorelik

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© 1989 Kluwer Academic Publishers, Dordrecht

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Flye, M.W. (1989). Metastatic Disease to the Lung in the Human. In: Gorelik, E.L. (eds) Metastasis / Dissemination. Cancer Growth and Progression, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2534-2_5

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  • DOI: https://doi.org/10.1007/978-94-009-2534-2_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7645-6

  • Online ISBN: 978-94-009-2534-2

  • eBook Packages: Springer Book Archive

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