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Abstract

Biosystems theory provides a useful framework for describing the biological role of bioactive compounds. Each functioning biosystem must adapt to and, to a certain degree, possess mechanisms or means to control both intra- and extra-­organism conditions, “purpose”. The organism must have the capabilities to change itself or the external environment, including community function, to achieve a purpose at the highest possible level. In general under adverse conditions, an organism is forced to renounce the purposes of higher level and to fulfill the purposes of a lower level. The achievement of higher level purposes depends on the production of natural bioactive compounds (adaptogens). The role of bioactive compounds is discussed herein from the point of general concept of biosystems, their resistance, and their adaptation to adverse conditions. Utilization of the concept of a biosystem will provide a clearer understanding of the role of bioactive compounds in the sustenance of an individual redox state and to predict new functions and properties of the organisms and their bioactive compounds.

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References

  1. Katano H (2000) Perspectives on systems biology. New Generation Comput 18:199–216

    Article  Google Scholar 

  2. Shmalgausen II (1968) The cybernetic problems of biology. Nauka, Novosibirsk

    Google Scholar 

  3. Bertalanffy L (1973) General theory (foundation, development, application). Brazilier G, New York

    Google Scholar 

  4. Patten BC (1971) A primer for ecological modeling and simulation with analog and digital computers. In: Systems analysis and simulation in ecology, vol 1. Academic, New York/London

    Google Scholar 

  5. Rosen R (1969) Principe of optimality in biology. Mir, Moscow

    Google Scholar 

  6. Rostopshin YA (1976) Mathematical modeling in physiology. Mathematical theory of biological processes. Nauka, Kaliningrad

    Google Scholar 

  7. Halliwell B (2006) Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. Plant Physiol 141:312–322

    Article  PubMed  CAS  Google Scholar 

  8. Bevan M, Bancroft I, Bent E et al (1998) Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. Nature 391:485–488

    Article  PubMed  CAS  Google Scholar 

  9. Shinozaki K, Yamaguchi-Shinozaki K (1997) Molecular responses to drought and cold stress. Curr Opin Biotechnol 7:161–167

    Article  Google Scholar 

  10. Pastori GP, Foyer CH (2002) Common components, networks, and pathways of cross-­tolerance to stress. The central role of “redox” and abscisic acid-mediated controls. Plant Physiol 129:460–468

    Article  PubMed  CAS  Google Scholar 

  11. Lazarev NV, Ljublina EI, Rozin MA (1959) State of nonspecific enhanced resistance. Patol Fiziol Exp Terap (Moscow) 3:16–21

    CAS  Google Scholar 

  12. Farmer EE (1994) Fatty acid signaling in plants and their associated microorganisms. Plant Mol Biol 26:1423–1437

    Article  PubMed  CAS  Google Scholar 

  13. Kleisig DF, Malamy J (1994) The salicylic acid signal in plants. Plant Mol Biol 26:1439–1458

    Article  Google Scholar 

  14. Musienko NN, Daskalyuk TM, Kaplia AV (1986) Growth response to high temperature in wheat seedlings. Plant Physiol (Russian) 33:134–141

    Google Scholar 

  15. Bar-Ness E, Chen Y, Hadar Y et al (1991) Siderphores of Pseudomonas putida as an iron source for dicot and monocot plants. Plant Soil 130:231–241

    Article  CAS  Google Scholar 

  16. Derylo M, Skorupska A (1992) Rhizobial siderophore as an iron source for clover. Physiol Plant 85:549–553

    Article  CAS  Google Scholar 

  17. Hamdan H, Weller DM, Thomashow LS (1991) Relative importance of fluorescent siderophores, and other factors in biological control of Gaeumannomyces gramminis var. Tritici by Pseudomonas fluorescens 2–79 and M4-8012. Appl Environ Microbiol 57:3270–3277

    PubMed  CAS  Google Scholar 

  18. Nietko KF, JrWT F (1989) Biosynthesis of cytokinins in soil. Soil Sci Soc Am J 52:735–740

    Article  Google Scholar 

  19. Bacon CW, Porter JK, Robbins JD et al (1977) Epichloe typhina from toxic tall fescue grasses. Appl Environ Microbiol 34:576–581

    PubMed  CAS  Google Scholar 

Download references

Acknowledgment 

The research described in this publication was made possible in part by the STCU Award No. 5063. Any opinions, findings and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect those of the STCU.

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Correspondence to Alexandru Dascaliuc .

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Dascaliuc, A., Ivanova, R., Arpentin, G. (2013). Systemic Approach in Determining the Role of Bioactive Compounds. In: Pierce, G., Mizin, V., Omelchenko, A. (eds) Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6513-9_10

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