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Metastatic Spinal Cord Compression from Synovial Sarcoma: Surgical Resection

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Tumors of the Central Nervous System, Volume 10

Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 10))

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Abstract

Synovial sarcoma is rare, and metastasis of synovial sarcoma to the spine is even rarer. Surgeons should have a high index of suspicion when evaluating patients who present with a history of synovial sarcoma, a spine lesion, and concomitant back pain and neurologic symptoms. Thorough radiological work-up should include CT and MRI in order to confirm the diagnosis and ensure appropriate management. Although not curative, surgical resection followed by spinal decompression, fusion, and fixation can lead to neurologic improvement in patients who present with spinal cord compression.

In this chapter, two illustrative cases are presented describing the surgical treatment of spinal cord compression caused by metastatic synovial sarcoma. The clinical presentation and prognostic factors of synovial sarcoma are discussed, as well as its cellular and histopathologic classification. Methods of diagnosis are described, which include histopathology, immunohistochemistry, and molecular studies, as well as the use of radiographs, CT, and MRI. Lastly, the treatment of both primary and metastatic synovial sarcoma is discussed, with sections on surgery, radiation, and chemotherapy.

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Authors and Affiliations

  1. Department of Neurosurgery, University of Kansas Medical Center, 3901 Rainbow Boulevard, Mail Stop 3021, Kansas City, KS, 66160, USA

    Karen K. Anderson & Paul M. Arnold

  2. Departments of Pathology and Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Mail Stop 3021, Kansas City, KS, 66160, USA

    Maura F. O’Neil

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  1. Karen K. Anderson
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  2. Paul M. Arnold
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  3. Maura F. O’Neil
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Editors and Affiliations

  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Anderson, K.K., Arnold, P.M., O’Neil, M.F. (2013). Metastatic Spinal Cord Compression from Synovial Sarcoma: Surgical Resection. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 10. Tumors of the Central Nervous System, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5681-6_32

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  • DOI: https://doi.org/10.1007/978-94-007-5681-6_32

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