Metastatic Spinal Cord Compression from Synovial Sarcoma: Surgical Resection

  • Karen K. Anderson
  • Paul M. Arnold
  • Maura F. O’Neil
Part of the Tumors of the Central Nervous System book series (TCNS, volume 10)


Synovial sarcoma is rare, and metastasis of synovial sarcoma to the spine is even rarer. Surgeons should have a high index of suspicion when evaluating patients who present with a history of synovial sarcoma, a spine lesion, and concomitant back pain and neurologic symptoms. Thorough radiological work-up should include CT and MRI in order to confirm the diagnosis and ensure appropriate management. Although not curative, surgical resection followed by spinal decompression, fusion, and fixation can lead to neurologic improvement in patients who present with spinal cord compression.

In this chapter, two illustrative cases are presented describing the surgical treatment of spinal cord compression caused by metastatic synovial sarcoma. The clinical presentation and prognostic factors of synovial sarcoma are discussed, as well as its cellular and histopathologic classification. Methods of diagnosis are described, which include histopathology, immunohistochemistry, and molecular studies, as well as the use of radiographs, CT, and MRI. Lastly, the treatment of both primary and metastatic synovial sarcoma is discussed, with sections on surgery, radiation, and chemotherapy.


Vertebral Body Soft Tissue Sarcoma Synovial Sarcoma Spinal Cord Compression Spinal Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Karen K. Anderson
    • 1
  • Paul M. Arnold
    • 1
  • Maura F. O’Neil
    • 2
  1. 1.Department of NeurosurgeryUniversity of Kansas Medical CenterKansas CityUSA
  2. 2.Departments of Pathology and Laboratory MedicineUniversity of Kansas Medical CenterKansas CityUSA

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